| DC22441 |
Eritoran tetrasodium |
Eritoran tetrasodium (E5564) is an investigational drug for the treatment of severe sepsis that acts as a TLR4 antagonist.. |
|
| DC26018 |
ERK5-IN-2
Featured
|
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. |
|
| DC22486 |
Erlotinib mesylate
Featured
|
Erlotinib is an epidermal growth factor receptor inhibitor (EGFR inhibitor). Erlotinib HCl was approved. Erlotinib binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. When erlotinib binds to EGFR, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated. |
|
| DCAPI1477 |
Ertapenem
Featured
|
Ertapenem is a carbapenem antibiotic marketed by Merck as Invanz. |
|
| DCAPI1476 |
Ertapenem Sodium
Featured
|
Ertapenem Sodium |
|
| DC7409 |
E-Mycin |
Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis. |
|
| DC20244 |
ES9-17
Featured
|
ES9-17 is a novel CME inhibitor. |
|
| DC10211 |
Escin |
Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut). |
|
| DC21000 |
ESI-05
Featured
|
ESI-05 is a potent EAPC2-specific antagonist that inhibits cAMP-mediated EPAC2 GEF activity with apparent IC50 of 0.43 uM. |
|
| DC8443 |
ESI-09
Featured
|
ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA. |
|
| DC9565 |
Eslicarbazepine (acetate) |
Eslicarbazepine acetate (BIA 2-093) is an antiepileptic drug.
|
|
| DC12325 |
Eslicarbazepine (BIA 2-194) |
Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures. |
|
| DCAPI1423 |
Esomeprazole |
Esomeprazole |
|
| DCAPI1487 |
Esomeprazole(magnesium) |
Esomeprazole(magnesium) |
|
| DC10714 |
Esonarimod (KE-298)
Featured
|
Esonarimod (KE-298) is a new antirheumatic drug. |
|
| DC23056 |
esperamicin A1
Featured
|
Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin. |
|
| DCAPI1200 |
Estradiol |
Estradiol |
|
| DC9440 |
Estropipate
Featured
|
Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis. |
|
| DC3162 |
Eszopiclone |
Eszopiclone is a nonbenzodiazepine hypnotic which is slightly effective for insomnia. |
|
| DC7770 |
Etamicastat |
Etamicastat is a novel dopamine β-hydroxylase inhibitor |
|
| DC21003 |
ETC-206
Featured
|
ETC-206 (ETC-1907206) is a novel potent, selective MNK1/2 inhibitor with IC50 of 64/86 nM, inhibits eIF4E phosphorylation inhibition in HeLa cell line with IC50 of 321 nM. |
|
| DC8123 |
ETH 157（Sodium ionophore II）
Featured
|
ETH 157（Sodium ionophore II）is a neutral ionophore for liquid-membrane electrodes of high selectivity for Na+. |
|
| DCAPI1235 |
Ethionamide |
Ethionamide |
|
| DC10267 |
Ethosuximide |
Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures. |
|
| DC12182 |
Ethyl docosa-4,7,10,13,16,19-hexaenoate |
Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol. |
|
| DC10046 |
Etizolam
Featured
|
Etizolam(AHR3219; Y7131) is a benzodiazepine analog. |
|
| DC7411 |
Etofenamate
Featured
|
Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain. |
|
| DC7124 |
ETP-46464
Featured
|
ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα, and ATM (IC50= 0.6, 14, 36, 170, and 545 nM, respectively). |
|
| DC9884 |
Etretinate |
Etretinate is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. |
|
| DC20376 |
Etriciguat |
Etriciguat is a novel potent, selective, orally available soluble guanylate cyclase (sGC) stimulator.. |
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