| DC9881 |
RHPS4
Featured
|
RHPS4 is a potent inhibitor of Telomerase at submicromolar. |
|
| DCAPI1165 |
Ribavirin (Copegus)
Featured
|
Ribavirin is a guanosine analog with antiviral properties against DNA and RNA viruses, including respiratory syncytial virus, hepatitis C, and influenza. |
|
| DC24015 |
Ribocil
Featured
|
Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB. |
|
| DC12237 |
Riboflavine phosphate (Riboflavine 5'-phosphate) |
Riboflavine phosphate is a very effective NAD+-recycling agent. |
|
| DCAPI1283 |
Rifapentine (Priftin) |
Rifapentine (Priftin) |
|
| DC23909 |
Rifaximin |
Rifaximin is an oral, semi-synthetic antibiotic derived from Rifamycin SV with antibacterial activity, interferes with transcription by binding to the β-subunit of bacterial RNA polymerase. |
|
| DCAPI1446 |
rifomycins |
rifomycins |
|
| DC24085 |
Rigosertib sodium
Featured
|
Rigosertib sodium (ON 01910.Na) is a potent, non-ATP-competitive PLK1 inhibitor (IC50=9-10 nM), selectively induces mitotic G2/M arrest and apoptosis in cancer cells. |
|
| DC8985 |
Riluzole
Featured
|
Riluzole is a glutamate antagonist used as an anticonvulsant and to prolong the survival of patients with amyotrophic lateral sclerosis. |
|
| DCAPI1057 |
Rimantadine (Flumadine) |
Rimantadine (Flumadine) |
|
| DC12800 |
BMS-927711(Rimegepant)
Featured
|
Rimegepant (BMS-927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM. |
|
| DC22089 |
Rimeporide (EMD-87580) |
Rimeporide (EMD87580) is a potent, selective sodium hydrogen exchanger NHE1 inhibitor, show promise as potential therapeutic agents for the treatment of heart failure.. |
|
| DC7267 |
Riociguat (BAY 63-2521)
Featured
|
Riociguat (BAY 63-2521) is a stimulator of soluble guanylate cyclase (sGC). |
|
| DC20535 |
RIP1-IN-22 |
RIP1-IN-22 is a highly potent, orally available, and brain-penetrating RIP1 kinase inhibitor with pKi of 9.04. |
|
| DC21945 |
RIPGBM |
RIPGBM is a cell type-selective, small molecule inducer of apoptosis in GBM cancer stem cells (CSCs) with EC50 of 220 nM (GBM 1 cells). |
|
| DC20536 |
RIPK2 inhibitor 1 |
RIPK2 inhibitor 1 is a novel potent, selective RIPK2 inhibitor with IC50 of 5-10 nM. |
|
| DC21946 |
RIPK2 inhibitor OD36 |
RIPK2 inhibitor OD36 is a potent, specific, ATP-competitive inhibitor of RIPK2 with IC50 of 5.3 nM, inhibits Tyr and Ser/Thr-directed activities of RIPK2. |
|
| DC21563 |
Risdiplam
Featured
|
Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA). |
|
| DC9049 |
Risedronate Sodium |
Risedronate sodium is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption. |
|
| DCAPI1012 |
Risedronic acid (Actonel) |
Risedronic acid (Actonel) |
|
| DC23619 |
Rislenemdaz hydrochloride |
Rislenemdaz (MK 0657. |
|
| DC23576 |
Rislenemdaz mesylate |
Rislenemdaz (MK 0657. |
|
| DC1064 |
RITA (NSC652287)
Featured
|
RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells. |
|
| DC21053 |
Rivipansel sodium |
Rivipansel sodium (GMI-1070, PF-06460031) is a novel small molecule glycomimetic pan-Selectin antagonist with IC50 of 4.3 uM, 423 uM and 337 uM for E-selectin, P-selectin and L-selectin, respectively. |
|
| DC23185 |
RJR-2403 oxalate |
RJR-2403 (Rivanicline, Metanicotine) is a potent, selective neuronal nicotinic ACh (nAChR) agonist with high affinity to rat brain cortex (Ki=26 nM), does not significantly activate muscle type nAChRs or muscarinic receptors. |
|
| DC23197 |
RJR-2403 |
RJR-2403 (Rivanicline, Metanicotine) is a potent, selective neuronal nicotinic ACh (nAChR) agonist with high affinity to rat brain cortex (Ki=26 nM), does not significantly activate muscle type nAChRs or muscarinic receptors. |
|
| DC12481 |
RK-20449 |
RK-20449 (RK20449) is a potent, small molecule inhibitor of hematopoietic cell kinase (HCK) with IC50 of 0.43 nM. |
|
| DC12436 |
RK-287107
Featured
|
RK-287107 (RK287107) is a novel potent, tankyrase-specific inhibitor with IC50 of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively, shows no activity against PARP-1. |
|
| DC9761 |
RK-33
Featured
|
RK-33 is a novel DDX3 inhibitor for lung cancer therapy. |
|
| DC23023 |
RNase L-IN-2 |
RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM. |
|
