| DC22638 |
RNPA1000 |
RNPA1000 is a potent, specific small molecule inhibitor of S. aureus RnpA RNA degradation activity (IC50=100-125 uM), limits S. aureus mRNA turnover and growth. |
|
| DC21569 |
RNPA2000 |
RNPA2000 is a small-molecule inhibitor of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing (IC50=130 uM). |
|
| DC23852 |
Ro 08-2750 |
Ro 08-2750 (Ro 082750) is a potent, selective, non-peptide nerve growth factor (NGF) inhibitor that binds to NGF dimer with Kd of 1 uM. |
|
| DC23321 |
RO 2443 |
RO 2443 is a potent, dual MDM2/MDMX antagonist that inhibits both MDM2 (IC50=33 nM) and MDMX (IC50=41 nM) binding to p53, but poor water solubility does not allow for a meaningful assessment of its cellular activity.. |
|
| DC22215 |
RO 27-3225
Featured
|
RO 27-3225 (RO27-3225, RO 273225) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM, >30-fold selectivity over MC3R. |
|
| DC21571 |
RO 28-2653 |
RO 28-2653 is a potent, selective and orally active matrix-metalloproteinases (MMPs) MMP2, MMP9 and MMP14 inhibitor with IC50 of 10, 12 and 10 nM, shows no activity against MMP3 and MMP1 (IC50>1 uM). |
|
| DC7933 |
Ro 48-8071 fumarate
Featured
|
Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity. |
|
| DC22214 |
Ro 60-0175 fumarate |
Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively. |
|
| DC22213 |
Ro 60-0175
Featured
|
Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively. |
|
| DC22427 |
Ro 64-6198 |
Ro 64-6198 is a nonpeptidic, selective, brain-penetrant agonist of nociceptin/orphanin FQ receptor (NOP receptor/ORL1) with pKi of 9.41. |
|
| DC7271 |
Ro3280
Featured
|
RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM. |
|
| DC8528 |
RO495
Featured
|
RO495 is a very potent TYK2 inhibitor with a IC50 of 1.5nM on TYK2 as tested in cell-based pharmacological assays |
|
| DC23601 |
RO-51 |
RO-51 is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.7 and 8.3, respectively.. |
|
| DC21575 |
RO5454291 |
RO5258638 is a small molecule inhibitor of CDK5-p25 protein-protein interaction with IC50 of 1.39 uM.. |
|
| DC21574 |
RO5258638 |
RO5258638 is a small molecule inhibitor of CDK5-p25 protein-protein interaction.. |
|
| DC21577 |
RO6889678 |
RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.. |
|
| DC21583 |
RO-7 |
RO-7 is a novel small molecule, broad-spectrum inhibitor of influenza acidic polymerase (PA) protein endonuclease activity with EC50 of 3.2-16 nM in MDCK cells. |
|
| DC20537 |
Robenacoxib
Featured
|
Robenacoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in veterinary medicine for the relief of pain and inflammation in cats and dogs, a Cyclooxygenase(COX)-1 and COX-2 inhibitor.. |
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|
| DC23888 |
Robotnikinin |
Robotnikinin is asmall molecule that binds the extracellular Sonic Hedgehog (Shh) protein (Kd=3.1 uM) and blocks Shh-signaling in cell lines, human primary keratinocytes and synthetic model of human skin. |
|
| DCAPI1424 |
Rocuronium Bromide |
Rocuronium Bromide |
|
| DC10759 |
Roflumilast N-oxide
Featured
|
Roflumilast N-oxide is a phosphodiesterase 4 inhibitor. Roflumilast N-oxide is the active metabolite of roflumilast. |
|
| DC20745 |
Rogaratinib
Featured
|
Rogaratinib (BAY 1163877) is a potent, selective, orally available pan-FGFR with IC50 of 15, <1, 19 and 33 nM for FGFR1, 2, 3 and 4, respectively. |
|
| DC23577 |
ROMK-IN-25 |
ROMK-IN-25 is a potent and selective ROMK channel (KCNJ1) inhibitor with IC50 of 72 nM. |
|
| DC23649 |
ROMK-IN-32 |
ROMK-IN-32 is a potent, selective ROMK inhibitor with IC50 of 17 nM. |
|
| DCAPI1439 |
Ropivacaine HCL
Featured
|
Ropivacaine Hydrochloride Monohydrate is used as a local anesthetic. |
|
| DC22834 |
Roseoflavin
Featured
|
Roseoflavin is a chemical analog of FMN and riboflavin that has antimicrobial activity. |
|
| DC23834 |
Rottlerin
Featured
|
Rottlerin (Mallotoxin. |
|
| DC23836 |
Roy-Bz |
Roy-Bz is the first small-molecule PKCδ-selective activator with EC50 of 58.5 nM, binds to the PKCδ-C1-domain. |
|
| DC11292 |
RP-1859 |
RP-1859 is a selective stimulator of S1P1 and S1P5 (S1P1 IC50 = 0.20 nM; S1P5 IC50 = 170 nM) used for the treatment of autoimmunity disease. |
|
| DC11293 |
RP-1865 |
RP-1865 is a selective stimulator of S1P1 and S1P5 used for the treatment of autoimmunity disease. |
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