DC9903 |
Saccharin 1-methylimidazole (SMI)
Featured
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SMI is considered a general-purpose activator for DNA and RNA synthesis. |
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DC21664 |
SMIFH2
Featured
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SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM. |
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DC7152 |
SMIP004 |
SMIP004 is a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, it was found to downregulate SKP2 and to stabilize p27. |
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DC22462 |
SMN2 modulator 27 |
SMN2 modulator 27 is a novel SMN2 modulator that stabilize the SMN protein with EC50 of 0.29 uM. |
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DC20553 |
SMN-C2 |
SMN-C2 is a close analogs of RG-7916 act as selective RNA-binding ligands that modulate pre-mRNA splicing. |
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DC20554 |
SMN-C3 |
SMN-C3 is a selective, orally available small molecule SMN2 splicing modifier toward the production of full-length SMN2 messenger RNA with high selectivity. |
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DC9531 |
SMND-309 |
SMND-309 is a novel derivative of salvianolic acid B, and has shown protective effects against rat cortical neuron damage in vitro and in vivo. |
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DC23887 |
M25 |
Smo antagonist M25 is a potent Smoothened (Smo) receptor antagonist (IC50=5 nM) that inhibits the Hedgehog signaling pathway. |
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DC20555 |
Smoothib |
Smoothib is a novel potent inhibitor of hedgehog (Hh) signaling (IC50=157±118 nM) and an antagonist of the protein smoothened (Smo), binds to the heptahelical bundle of Smo with Kd of 59 nM. |
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DC12500 |
SN-6
Featured
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SN-6 is a selective Na+/Ca2+exchange (NCX) inhibitor, displaying some selectivity for NCX1. |
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DC12597 |
SN79 dihydrochloride |
SN79 dihydrochloride (Sigma receptor ligand SN79) is a putative σ receptor antagonist with nanomolar affinity and selectivity for σ receptors over 57 other binding sites. |
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DC21670 |
SNAP-7941 |
SNAP-7941 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 15 nM. |
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DC21671 |
SNAP-94847 |
SNAP-94847 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 1.69 nM. |
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DC21672 |
SNAP-94847 hydrochloride
Featured
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SNAP-94847 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 1.69 nM. |
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DC22792 |
SNIPER(AR)-51 |
SNIPER(AR)-51 is a specific and nongenetic, protein degradation inducer of androgen receptor, consistiong of AR ligand and IAP ligand and linker. |
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DC21953 |
SNIPER(ER)-110 |
SNIPER(ER)-110 is a nongenetic IAP-dependent protein eraser (SNIPER) targeting estrogen receptor α (ERα), induces ERα degradation and induces apoptosis in MCF-7 human breast cancer cells. |
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DC10488 |
SNS-062
Featured
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SNS-062 is a non-covalently binding inhibitor of Bruton's tyrosine kinase (BTK). |
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DC11318 |
SNVP |
SNVP is an S-nitrosothiol that acts as a nitric oxide (NO) donor and vasodilator. |
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DC21674 |
SNX-0723 |
SNX-0723 is a selective, brain-permeable, orally acitve small-molecule inhibitor of Hsp90 (IC50=14 nM) that inhibits alpha-synuclein oligomerization with EC50 of 48 nM. |
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DC23803 |
SNX-9114 |
SNX-9114 (SNX9114, PF-04944733) is a small molecule Hsp90 inhibitor with excellent brain permeability.. |
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DC9539 |
Sobetirome
Featured
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Sobetirome(GC-1; QRX-431) is a member of a class of compounds known as selective thyromimetics. |
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DC11020 |
SOD1-Derlin-1 inhibitor 56-59 |
SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assay. |
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DC9540 |
sodium 4-pentynoate |
sodium 4-pentynoate is a alkynylacetate analogue; can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types. |
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DC20213 |
Sodium L-lactate |
Sodium L-lactate is used as a food additive, preservative, acidity regulator and bulking agent. |
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DC8920 |
Sodium picosulfate |
Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion. |
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DC10249 |
Sodium sulfadiazine |
Sodium Sulfadiazine is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative. |
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DC9502 |
Solifenacin (hydrochloride)
Featured
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Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.
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DC8800 |
Solifenacin Succinate
Featured
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Solifenacin Succinate(YM905; Vesicare) is a muscarinic receptor antagonist. |
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DCAPI1292 |
Sophocarpine |
Sophocarpine |
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DC22778 |
Sortin1 |
Sortin1 is a small molecule sorting inhibitor (Sortin) that induces reversible defects in vacuole biogenesis and root development in Arabidopsis seedlings at 100 mg/liter (227 uM). |
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