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Cat. No.	Product Name	Field of Application
DC11101	Soticlestat Featured	Soticlestat is a potent, selective cholesterol 24-hydroxylase inhibitor.
DC20634	Sovaprevir	Sovaprevir (ACH-1625, ACH-0141625) is a potent HCV NS3/4A inhibitor in development for the treatment of hepatitis C..
DC21675	SP 4206	SP 4206 is a high-affinity (Kd=70 nM) small molecule that blocks blocks the binding of the IL-2α receptor (IL-2Rα) to IL-2.
DC8039	SP-420 Featured	SP-420 is an orally active small molecule that selectively binds iron and removes it from the body. SP-420 has shown excellent tissue penetration, highly efficient iron binding and a promising safety profile.
DC21676	SPA70	SPA70 is a potent and selective hPXR antagonist (IC50=0.51 uM) that interacts with the ligand-binding domain (LBD) of hPXR, inhibits hPXR in human hepatocytes and mouse models and enhances the chemosensitivity of cancer cells.
DC10405	SPACE peptide	SPACE peptide is a skin penetrating peptide which facilitates the delivery of molecules through the skin.
DC26007	Spastazoline Featured	Spastazoline is a potent and selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC50 of 99 nM for Human spastin. Spastazoline shows no effect on ATPase activity of a recombinant human VPS4.
DC20139	SPD304 Featured	SPD304 is a selective inhibitor of tumor necrosis factor α (TNFα) and promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor, with an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α.
DC24125	SPDB Featured	SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs)..
DC22231	Sphynolactone-7	Sphynolactone-7 (SPL7) is a potent, specific, femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica with minimum effective concentration (MEC) of 10 fM that produces any seed germination.
DC12592	SPL7	Sphynolactone-7 (SPL7) is a potent, specific, femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica with minimum effective concentration (MEC) of 10 fM that produces any seed germination.
DC10587	SPI 112 Featured	SPI 112 is novel Shp2 PTP inhibitor.
DC21677	SPI009	SPI009 is a novel antipersister compound active against P. aeruginosa.
DC10690	SPI-112Me Featured	SPI-112Me is a prodrug for SPI-112, which preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by a factor of 20 in cell-free assays.
DC21768	Spiradoline	Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects..
DC21769	Spiradoline mesylate	Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects..
DC8708	Spirodiclofen	Spirodiclofen is a broad spectrum acaricide acting via lipid biosynthesis inhibition (LBI) with no cross resistance to currently available acaricides and with additional insecticidal properties.
DC22232	Spiropiperidine 1	Spiropiperidine 1 (SPP1)i s a potent, functionally selective and brain penetrant M1 orthosteric agonist with Ki of 21.3 nM for hM1 receptors.
DC12551	SPP1	Spiropiperidine 1 (SPP1)i s a potent, functionally selective and brain penetrant M1 orthosteric agonist with Ki of 21.3 nM for hM1 receptors.
DC21678	SPL-707	SPL-707 (SPL707) is the first selective, orally active signal peptide peptidase-like 2a (SPPL2a) inhibitor with IC50 of 77 nM, shows 25-fold selectivity over γ-secretase and SPP.
DC23750	Spliceostatin A Featured	Spliceostatin A is a methylated derivative of FR-901464 that inhibits pre-mRNA splicing.
DC20556	SPOP-IN-6b	SPOP-IN-6b is a potent, small-molecule E3 Ligase adaptor SPOP (speckle-type POZ protein) inhibitor that inhibits the SPOP-substrate protein interaction with IC50 of 35 uM (inhibits puc-SBC1 peptide binding to SPOP).
DC11300	SPR-00305	SPR-00305 is a potent MvfR inhibitor and displays target engagement.
DC21682	SPRi3	SPRi3 (SPR inhibitor 3) is a small molecule inhibitor of sepiapterin reductase (SPR) with IC50 of 74 nM in cell-free assays, efficiently reduces biopterin levels with IC50 of 5.2 uM.
DC23399	SPV 106	SPV 106 is the first mixed activator/inhibitor of Histone acetyltransferases (HATs), potentiates p300/CBP-associated factor (PCAF) HAT activity while inhibiting those of p300/CBP and recombinant CBP.
DC23580	SPX-101	SPX-101 is a specific, peptide mimetic promoter of epithelial sodium channel (ENaC) internalization, binds selectively to ENaC and promotes internalization of the α-, β-, and γ-subunits.
DC8135	NB598	Squalene epoxidase inhibitor. Suppresses triglyceride biosynthesis through the farnesol pathway.
DC11412	SR 0987 Featured	SR 0987 is an agonist of the T cell-specific isoform of RORγ (RORγt, retinoic acid receptor-related orphan receptor-γt), inducing reporter gene expression with an EC50 value of ~800 nM.
DC26062	SR 16832	SR 16832 is a dual-site covalent antagonist of peroxisome proliferator-activated receptor γ (PPARγ).
DC21692	SR 9444	SR 9444 is a small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK with IC50 of 12 nM and 99 nM respectively.

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