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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC8721 Sirtinol Featured Sirtinol is a cell-permeable, specific inhibitor of sirtuin NAD-dependant histone deacetylases.
DC9898 SIS3 Featured SIS3 is a potent and selective inhibitor of Smad3. a potent regulator of the human Nox4 promoter.
DCAPI1086 Sitafloxacin hydrate Featured Sitafloxacin Hydrate is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.
DC5112 Sitagliptin (Metformin,MK-0431) Sitagliptin phosphate (MK-0431) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.
DC10901 SJ000291942 Featured SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are members of the transforming growth factor beta (TGFβ) family of secreted signaling molecules.
DC20591 SJ-733 SJ-733 (SJ000557733.
DC21654 SJ830599 SJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1.
DC26019 SJA710-6 Featured SJA710-6 (a Hepatic Differentiation Inducer) is a novel, potent and cell-permeable small molecule imidazopyridinamine compound that is able to induce the differentiation of rat MSCs (rMSCs) toward hepatocyte-like cells (~47% at 5 µM).
DC21655 SJB7 Featured SJB7 is a close analog of SPA70 and hPXR agonist, interacts with the ligand-binding domain (LBD) of hPXR..
DC22450 SK 216 SK 216 is a potent, selective inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 44 uM.
DC23427 SK609(SK-609;SK 609;ES609) SK609 (SK-609, ES609) is a potent, selective agonist of dopamine D3 receptor with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation.
DC20104 Skatole Featured Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
DC7765 Skepinone-L Featured Skepinone-L is a selective p38α-MAPK inhibitor with IC50 of 5 nM.
DC23451 SKF-38393 hydrobromide SKF-38393 is a potent, selective D1/D5 receptor partial agonist with Ki of 1 and 0.5 nM, respectively.
DC21659 SKI-178 Featured SKI-178 is a potent, specific, non-lipid SphK1 inhibitor with Ki of 1.33 uM, displays no significant activity for SphK2 (IC50>25 uM).
DC21660 SKLB188 SKLB188 is a novel multikinase inhibitor and potently inhibits EGFR with IC50 of 5 nM.
DC12619 SKLB-C05 SKLB-C05 is a novel selective, orally active TOPK inhibitor with IC50 of 0.5 nM, shows excellent cytotoxicity and anti-migration and invasion activity on TOPK high-expressing CRC cells and induces cell apoptosis.
DC8500 SKQ1(Visomitin) Featured SKQ1 prevents amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices.
DC8740 SL327 Featured SL-327 is a cell-permeable vinylogous cyanamide that acts as a selective inhibitor of MEK-1 and MEK-2 (IC50 = 0.18 and 0.22 μM respectively).
DC20552 SLC25A20-IN-21 SLC25A20-IN-21 is a SLC25A20 ligand that increases long-chain (>C14) acylcarnitine content and reduces maximal exogenous fatty acid oxidation in HSC-5 cells.
DC12314 SLLK, Control Peptide for TSP1 Inhibitor(TFA) Featured SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor.
DC22005 SLLN-15 SLLN-15 (Autophagy inducer SLLN-15) is a potent, orally available inducer of autophagy that selectively activated cytostatic macroautophagy/autophagy in TNBC preclinical models, promotes AURKA degradation and .
DC23294 SM-1295 SM-1295 is a potent, selective cIAP1 and cIAP2 inhibitor with Ki of <10 nM, displays >900-fold for cIAP1 over XIAP.
DC23295 SM13 SM13 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo.
DC8490 SM-164 Featured SM-164 is a bivalent mimetic of Smac with Ki values of 0.31 nM, 1.1 nM and 0.56 nM for cIAP-1, cIAP-2 and XIAP, respectively
DC22723 SM-324405 SM-324405 is a potent, selective TLR7 agonist with EC50 of 50 nM, induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, inhibits IL-5 production in human PBMCs in vitro..
DC22537 SMAP Featured SMAP (DT-061, DT061) is an orally bioavailable small molecule activator of PP2A, inhibits KRAS-driven tumor growth.
DC21662 SMAP-2 SMAP-2 (DT-1154) is an orally bioavailable small molecule activator of PP2A, binds to PP2A Aα scaffold subunit and inhibits KRAS-driven tumor growth both in vitro and in vivo.
DC20762 SMARt-420 SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice, also increases the basal sensitivity of bacteria to ethionamide..
DC7895 SMER3(SMER 3) SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo.

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