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Cat. No. Product Name Field of Application Chemical Structure
DC22722 T5342126 T5342126 is a potent, selective TLR4 inhibitor, inhibits LPS-induced NO production in RAW 264 macrophage cells with IC50 of 27.8 uM.
DC12534 T5910047 Featured T5910047 (T-5910047) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation; inhibits SEB-induced inhibition of cytokine production in PBMCs with IC50 of 2-10 uM, also inhibits SEA-induced pro-inflammatory cytokine production, shows no toxicity in primary cells up to 100 uM.
DC12533 T6167923 T6167923 (T-6167923) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation.
DC22299 Tabersonine Featured Tabersonine is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus.
DC10756 PF-06291826(Tafamidis) Featured Tafamidis is a novel specific transthyretin (TTR) stabilizer or dissociation inhibitor.
DC12377 Tafamidis meglumine Featured Tafamidis is a novel specific transthyretin (TTR) stabilizer or dissociation inhibitor.
DC21609 Tafenoquine Featured Tafenoquine (SB-252263, Tafenoquine, WR 238605) is a long-acting, orally active anti-malarial agent to prevent malaria that is holoendemic for Plasmodium falciparum..
DC21610 Tafenoquine succinate Featured Tafenoquine succinate (SB-252263, Tafenoquine, WR 238605) is a long-acting, orally active anti-malarial agent to prevent malaria that is holoendemic for Plasmodium falciparum..
DC21725 TAI-95 TAI-95 (TAI 95) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines).
DC7822 TAK1 inhibitor(compound 13a) TAK 1 inhibitor
DC21729 TAK-100 TAK-100 is a potent, selective and orally active inhibitor of DPP-4 with IC50 of 5.3 nM, shows no inhibition on DPP2/8/9..
DC20563 TAK1-IN-1 TAK1-IN-1 is a potent, selective, Type I (ATP-competitive, DFG-in) TAK1 inhibitor with Kd of 59 nM, a thienopyrimidine scaffold that serves as a good starting point for medicinal chemistry..
DC7923 TAK-599 (ceftaroline fosamil) Featured TAK-599 is a highly promising parenteral cephalosporin targeted for MRSA infection.
DC21280 TAK-659 free base(Mivavotinib) Featured TAK-659 (TAK659, Mivavotinib) is a potent, selective and orally available SYK inhibitor with IC50 of 3.2 nM.
DC8880 Orteronel (TAK-700) TAK-700 shows potent inhibitory activity against rat, monkey, and human steroid 17,20-lyase inhibitor with IC50 of 54 nM, 27 nM, and 38 nM, respectively.
DC20048 TAK-828F TAK-828F is a potent, selective, and orally available retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist (binding IC50=1.9 nM, reporter gene IC50=6.1 nM). TAK-828F shows excellent ROR isoforms selectivity (>5000-fold selectivity aga
DC21653 Simurosertib (TAK-931) Featured TAK-931 (Simurosertib) is a potent, selective, ATP competitive and orally bioavailable inhibitor of Cdc7 with IC50 of <0.3 nM.
DC7309 TAK-960 Featured TAK-960 is a novel, potent and selective Polo-like kinase 1 (PLK1) inhibitor.
DC23153 Talabostat Talabostat (PT-100, Val-boroPro) is a potent, nonselective, orally available inhibitor of post-proline cleaving serine proteases with Ki of 0.18 nM for DPP4, also potently inhibits DPP8/9 (IC50=1.5/0.76 nM), FAP, DPP2 and some other DASH family enzymes.
DC7310 Tamibarotene(Am-80) Featured Tamibarotene(Am-80) is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro.
DC23853 TAM-IN-1 TAM-IN-1 is a highly potent, macrocyclic inhibitor of Mer and Axl with Ki of <50 pM and 130 pM, respectively..
DC21957 Taminadenant Taminadenant is an adenosine receptor A2a antagonist..
DC9096 Tamoxifen Featured Tamoxifen(ICI-46474) is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen.
DC9145 Tamsulosin hydrochloride Tamsulosin hydrochloride((R)-(-)-YM12617;LY253351) is a selective α1 receptor antagonist.
DC23076 Tanshinone I Featured Tanshinone I is an inhibitor of type IIA human recombinant sPLA2 (IC50=11 μM) and rabbit recombinant cPLA2 (IC50=82 μM).
DC23815 TAO Kinase inhibitor 1 Featured TAOK inhibitor 43 is a novel potent, selective, ATP-competitive TAO Kinase (TAOK) inhibitor with IC50 of 11 and 15 nM against TAOK1 and TAOK2, respectively; increases the mitotic population, the percentages of mitotic cells displaying amplified centrosomes and multipolar spindles, induces cell death, and inhibits cell growth in centrosome-amplified SKBR3 or BT549 breast cancer cell models.
DC23809 TAOK inhibitor 63 TAOK inhibitor 63 is a novel potent, selective, ATP-competitive TAO Kinase (TAOK) inhibitor with IC50 of 19 and 39 nM against TAOK1 (MAP3K16) and TAOK2 (MAP3K17), respectively.
DC21732 TAP-311 TAP-311 is a novel potent and selective CETP inhibitor with plasma IC50 of 62 nM.
DC7560 TAPI-1 TAPI-1 is a specific TACE(TNF-α-converting enzyme) inhibitor.
DC7207 Tarafenacin(SVT-40776) Tarafenacin(SVT-40776) is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over M2 receptor.

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