Other Targets

You can also try the following methods, and our professionals will serve you Customized Consultation

Cat. No.	Product Name	Field of Application
DC21711	SUVN-502 mesylate	SUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
DC21712	SUVN-502 mesylate hydrate	SUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
DC21713	SUVN-502	SUVN-502 (SUVN502, Masupirdine) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
DC22239	SUVN-G3031 dihydrochloride	SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R).
DC22238	SUVN-G3031 Featured	SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R).
DC23819	SW-034538	SW-034538 is a potent TAOK2 (Thousand-And-One Kinase 2.
DC21714	SW-083688	SW-083688 (SW083688) is a potent, highly selective TAOK2 (Thousand-And-One Kinase 2, MAP3K17) inhibitor with IC50 of 1.3 uM.
DC12634	SW-100 Featured	SW-100 (SW100) is a potent, selective, brain penetrable HDAC6 inhibitor with IC50 of 2.3 nM, displays >1,000-fold selectivity over all other class I, II, and IV HDAC isoforms.
DC21715	Gliocidin Featured	Gliocidin is a prodrug that is anabolized into its tumoricidal metabolite, gliocidin–adenine dinucleotide (GAD). Gliocidin kills glioblastoma cells while sparing non-tumour replicative cells. Gliocidin activity targets a de novo purine synthesis vulnerability in glioblastoma through indirect inhibition of inosine monophosphate dehydrogenase 2 (IMPDH2). Gliocidin penetrates the blood–brain barrier and extends the survival of mice with orthotopic glioblastoma.
DC20117	SW-163D-AcLysValCit-PABC-DMAE	SW-163D-AcLysValCit-PABC-DMAE is a Drug-Linker Conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker.
DC24205	SY-1365 Featured	SY-1365 is a CDK7 inhibitor. In vitro, SY-1365 inhibited cell growth of many different cancer types at nanomolar concentrations.
DC22240	SYC-435	SYC-435 (SYC435) is a potent inhibitor of mutant IDH1, binds at the isocitrate pocket of mutated IDH1 with Ki values of 190 nM against IDH1 R132H and 120 nM against IDH1 R132C.
DC10900	Syk inhibitor II Featured	Syk inhibitor II is a cell-permeable, pyrimidine-carboxamide compound that selectively and reversibly blocks Syk (IC50 = 41 nM) in an ATP-competitive manner.
DC23846	Syk-IN-23	Syk-IN-23 is a potent, selective Syk kinase inhibitor with IC50 of 20 nM, possesses good PK in both rat and dog and demonstrated efficacy in rat CIA model..
DC20562	Syn-TEF1 intermediate 1	Syn-TEF1 intermediate 1 is a chemcal intermediate for Syn-TEF1 synthesis, which is a molecule actively enables transcription across repressive GAA repeats that silence frataxin expression in Friedreich's ataxia..
DC20561	Syn-TEF1	Syn-TEF1 is a molecule actively enables transcription across repressive GAA repeats that silence frataxin expression in Friedreich's ataxia, license transcription elongation at targeted genomic loci.
DC12418	SynuClean-D	SynuClean-D (SC-D) is a novel, small molecule inhibitor of α-synuclein (α-Syn) aggregation, incubation of 70 uM α-Syn with 100 uM SC-D impacted α-Syn aggregation in vitro, as monitored by Th-T fluorescence.
DC22242	T-025	T-025 (T025, CLK inhibitor T-025) is an orally available, potent inhibitor of Cdc2-like kinases (CLKs) with Kd of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, also inhibits DYRK1A and DYRK1B with IC50 of 0.074 and 1.5 nM.
DC21719	T-1105	T-1105 is a broad-spectrum antiviral inhibitor that demonstrates good activity for various RNA viruses, including influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), FMDV, and ZIKV.
DC21720	T-155535	T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.
DC21956	T16Ainh-A01 Featured	T16Ainh-A01 is an inhibitor of the calcium-activated chloride channel TMEM16A, inhibits Ca2+-activated Cl− channel (CACC) activity in TMEM16A-transfected FRT cells with IC50 of 1 uM; T16Ainh-A01 (1-30 uM) inhibited single calcium (Ca2+)-activated chloride (Cl−) channels and whole cell currents activated by 500 nM free Ca2+; T16Ainh-A01 relaxed mouse thoracic aorta pre-contracted with methoxamine with an IC50 of 1.6 uM and suppressed the methoxamine concentration-effect curve; blocks calcium-activated chloride channels in vascular smooth muscle cells and relaxes murine and human blood vessels.
DC26101	T-1840383	T-1840383 is a potent, ATP-competitive, dual c-Met/VEGFR-2 inhibitor with IC50 of 1.9, 7.7, 2.2 and 5.5 nM for c-Met, VEGFR1, 2 and 3, respectively.
DC21721	T-226296	T-226296 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) with IC50 of 5.5 nM and 8.6 nM for human and rat MCHR1, respectively.
DC20124	T-26c Featured	T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes.
DC21723	T-3861174	T-3861174 is a novel small molecule prolyl tRNA synthetase (PRS) with binding IC50 of 2.3 nM.
DC21724	T3D-959	T3D 959 (DB-959) is a potent, brain penetrant, orally active dual PPARδ/PPARγ agonist with EC50 of 19/297 nM, respectively.
DC12606	T-448 Featured	T-448 (T448) is a specific inhibitor of LSD1 enzyme activity, enhances H3K4 methylation in primary cultured rat neurons but has little impact on LSD1-GFI1B complex in human TF-1a erythroblasts.
DC12607	T-448 free base	T-448 free base (T448) is a specific inhibitor of LSD1 enzyme activity, enhances H3K4 methylation in primary cultured rat neurons but has little impact on LSD1-GFI1B complex in human TF-1a erythroblasts.
DC23327	T-521	T-521 is a novel PLK1 PBD (Polo-box domain) inhibitor that specifically inhibits the PBD of PLK1 (IC50=1.22 uM), but not those of Plk2-3.
DC22725	T5342126 hydrochloride	T5342126 hydrochloride is a potent, selective TLR4 inhibitor, inhibits LPS-induced NO production in RAW 264 macrophage cells with IC50 of 27.8 uM.

Other Targets

Customized Consultation X

Your information is safe with us. * Required Fields.