Tamibarotene(Am-80)

  Cat. No.:  DC7310   Featured
Chemical Structure
94497-51-5
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Field of application
Tamibarotene(Am-80) is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro.
Cas No.: 94497-51-5
Chemical Name: Tamibarotene
Synonyms: 4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoic acid;AM80;4-[(5,5,8,8-Tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid;4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic Acid;Am 80 (pharmaceutical);Amnolake;NSC 608000;Retinoid AM 80;Tamibarotene;Am-80;TAMIBAROTENE,AM 80,AM-80,AM80;4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoicacid;Am 80;retinobenzoic acid;Tamibaro;Amnoid;4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid;08V52GZ3H9;NSC608000;4-((5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl)benzoic acid;4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid (ACI);4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid;Am 80 (RAR agonist);INNO 507;OP 01;RR 110;SY 1425;TM 441;TOS 80T
SMILES: O=C(C1C=CC(C(NC2C=C3C(CCC(C3=CC=2)(C)C)(C)C)=O)=CC=1)O
Formula: C22H25NO3
M.Wt: 351.438806295395
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity For RARα and RARβ over RARγ.For the detailed information of Tamibarotene(Am-80), the solubility of Tamibarotene(Am-80) in water, the solubility of Tamibarotene(Am-80) in DMSO, the solubility of Tamibarotene(Am-80) in PBS buffer, the animal experiment (test) of Tamibarotene(Am-80), the cell expriment (test) of Tamibarotene(Am-80), the in vivo, in vitro and clinical trial test of Tamibarotene(Am-80), the EC50, IC50,and Affinity of Tamibarotene(Am-80), Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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