DC10281 |
Terconazole |
Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection. |
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DC9155 |
Terfenadine |
Terfenadine is a potent open-channel blocker of hERG with a mean IC50 of 204 nM. |
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DC4221 |
Teriflunomide(A-771726)
Featured
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Teriflunomide: Teriflunomide, aslo know as A77 1726 (trade name Aubagio, marketed by Sanofi) is the active metabolite of leflunomide. |
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DC21958 |
tert-butyl 2-cyano-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate |
tert-butyl 2-cyano-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate.. |
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DC22245 |
TES-1025
Featured
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TES-1025 (TES1025) is a potent, selective inhibitor of human ACMSD (α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase) with IC50 of 13 nM, increases NAD+ levels in cellular systems. |
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DC12150 |
TES-991 |
TES-991 is a potent and selective human α‑Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) inhibitor, with an IC50 of 3 nM. |
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DC7316 |
Tesmilifene |
Tesmilifene is a novel agent that augments cytotoxicity of various chemotherapeutic agents both in vitro and in vivo. It binds selectively to the high-affinity microsomal antiestrogen binding site (Ki=50nm) but has no affinity for estrogen receptors. Inhi |
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DC23675 |
Tetomilast |
Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release. |
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DC9866 |
Tetrabenazine
Featured
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Tetrabenazine has been used for dopamine uptake assays in mouse brain cells1. |
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DC9041 |
Tetracaine HCl |
Tetracaine HCl is a potent local anaesthetic and a channel function allosteric inhibitor. |
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DCAPI1291 |
Tetracycline HCl |
Tetracycline HCl |
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DC12218 |
Tetradecanoylcarnitine
Featured
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Tetradecanoylcarnitine is a human carnitine involved in β-oxidation of long-chain fatty acids. |
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DCAPI1289 |
Tetrahydropapaverine HCl |
Tetrahydropapaverine HCl |
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DC9374 |
6-TAMRA |
Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. |
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DC9361 |
Tetramisole (hydrochloride) |
Tetramisole hydrochloride is an inhibitor of alkaline phosphatases, is a high purity antiparasitic.
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DC23911 |
Tetrodotoxin citrate |
Tetrodotoxin (TTx) is a potent, highly selective sodium channel blocker with IC50 of 33 nM for Nav1.6. |
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DC21252 |
Tezampanel |
Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor. |
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DC8932 |
TG003
Featured
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TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC. |
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DC22308 |
TG4-155
Featured
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TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. It blocks the induced expression of inflammatory markers in microglial cells. |
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DC21748 |
TG693
Featured
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TG693 is an orally available, selective, ATP-competitive CLK1 inhibitor with IC50 of 112.6 nM. |
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DC12506 |
TG8-69
Featured
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TG8-69 is a peripherally restricted, highly potent, selective, aqueous-soluble EP2 antagonist with Kb of 48.5 nM. |
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DC7559 |
TGF-B (beta) receptor inhibitor
Featured
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TGF-β receptor inhibitor |
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DC12042 |
TGN-020
Featured
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TGN 020 is a thiadiazole derivative studied for its potential antitumor properties |
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DC25110 |
TGR-1202 R-enantiomer |
TGR-1202 R-enantiomer is is the less active enantiomer of TGR-1202 (Umbralisib), TGR-1202 is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 22 nM.. |
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DC21750 |
TH 5427 |
TH 5427 (TH5427) is a potent, small molecule NUDT5 (NUDIX5) inhibitor with IC50 of 29 nM, 690-fold selectivity for NUDT5 over MTH1 (NUDT1) in vitro. |
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DC12564 |
TH-257
Featured
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TH-257 (TH257) is a potent, selective, allosteric inhibitor of LIMK1 and LIMK2 with IC50 of 84 nM for LIMK1 and 39 nM for LIMK2 in a RapidFire MS assay. |
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DC23145 |
TH5487
Featured
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TH5487 (TH-5487, TH 5487) is a potent, selective, active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 342 nM, prevents OGG1 from binding to its DNA substrate. |
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DC26123 |
Thalidomide-O-amido-C3-NH2 |
Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC26125 |
Cereblon Ligand-Linker Conjugates 3 (TFA)
Featured
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Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. |
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DC20289 |
(1S,2S)-2-PCCA |
The (1R,2R) diastereomer of 2-PCCA, a potent, selective agonist of the orphan GPR88 receptor with EC50 of 373 nM, 5-fold more potent than the (1S, 2S)-isomer.. |
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