DC33479 |
5-Hydroxy-1H-indole-3-ethanol |
Hydroxytryptophol is a serotonin/melatonin analog found in various plant and food soruces and Trypanosoma brucei. It is used as a biomarker for recent alcohol consumption and causes sleeping sickness. It also inhibits oxidation of LDL. |
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DC33480 |
1-Isothiocyanato-3-(methylthio)propane |
Iberverin is a sulforaphane homolog and antioxidant found in cruciferous vegetables. It induces phase II enzyme activity and decreases expression of androgen receptors in prostate cancer cells. |
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DC33481 |
Imazalil |
Enilconazole, also known as Imazalil, is an inhibitor of 14α-demethylase, aromatase, and androgen receptors that inhibits ergosterol synthesis and fungal cell wall formation. It also alters neural differentiation and displays teratogenic effects in vertebrate development. |
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DC33482 |
Indinavir Sulfate |
Indinavir sulfate is an inhibitor of HIV protease, GLUT4, and calpain used to treat HIV infection. It also decreases phosphorylation of the insulin receptor β subunit, inhibits adenocarcinoma tumor growth, and may induce SOCS1 signaling. |
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DC33483 |
Inosite |
Inositol, also known as myo-Inositol, is an endogenous sugar produced from glucose that is required for production of IMP and phosphatidyl inositol. It is involved in insulin sensitivity and glucose disposal. |
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DC33486 |
Isopropy-beta-D-thiogalactopyranoside |
Isopropyl thiogalactoside is a galactose and allolactose mimic that induces activation of lac operon, stimulating protein expression. |
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DC33487 |
HSR 803 hydrochloride |
Itopride HCl is an AChE inhibitor and dopamine D2 receptor antagonist used to treat functional dyspepsia and gastroesophageal reflux disease. It inhibits lower esophageal sphincter relaxation. |
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DC33488 |
HSR 803 |
Itopride HCl is an AChE inhibitor and dopamine D2 receptor antagonist used to treat functional dyspepsia and gastroesophageal reflux disease. It inhibits lower esophageal sphincter relaxation. |
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DC33489 |
K252b |
K252b is a staurosporine analog and PKC inhibitor that suppresses DNA synthesis. It also inhibits microbial ectoprotein kinases and inhibits IgE cross-linking-dependent degranulation in basophils. |
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DC33490 |
staurosporine aglycone |
K252c is a staurosporine analog and inhibitor of PKC and PKA. It inhibits proliferation of human cytomegalovirus and induces apoptosis in cancer cells. |
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DC33491 |
CCRIS 1521 |
Kahweol is a natural product in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress. |
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DC33492 |
Kahweol acetate |
Kahweol Acetate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress. |
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DC33493 |
Kahweol Eicosanate |
Kahweol Eicosanate is a semi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress. |
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DC33494 |
Kahweol oleate |
Kahweol oleate is emi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress. |
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DC33495 |
Kahweol palmitate |
Kahweol palmitate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1-induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress. |
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DC33496 |
Digenin |
Kainic acid is an excitatory amino acid and AMPA and kainate receptor agonist found in seaweed. It increases glutamate release and stimulates Na channels, inducing seizures. |
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DC33497 |
Bekanamycin |
Kanamycin B is an inhibitor of protein translation and mammalian RNA splicing. It inhibits growth of gram negative bacteria, prevents formulation of the initiation complex, and decreases action potential amplitude in cardiac pacemaker cells. |
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DC33498 |
Lactacystin |
Lactacystin is a proteasome inhibitor found in Streptomyces. It increases the Bax/Bcl-2 ratio and inhibits proliferation of glioma cells, inhibits growth and migration of smooth muscle cells, and suppresses infiltration of neutrophils and decreases levels of ICAM-1 in liver injury models. |
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DC33500 |
(d)-Limonene |
(d)-Limonene is a commercial flavorant, odorant, cleaning solvent, and insecticide found in the rind of various citrus plants. It displays a wide range of activities, including cell cycle arrest and apoptosis in gastric carcinoma cells, inducing phase II enzyme expression to limit oxidative damage, and suppressing cytokine production by CD4+ and CD8+ T cells. |
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DC33501 |
CCRIS 6986 |
Limonin glucoside is found in citrus fruits. It induces apoptosis in colon adenocarcinoma cells, inhibits expression of HIV-1 and HTLV-1 in infected cells, and exhibits larvicidal activity against species of Aedes. |
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DC33502 |
Lincocin |
Lincomycin hydrochloride is a peptidyl transferase and protein translation inhibitor used to treat bacterial infections. It also inhibits growth of plasmodium. |
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DC33503 |
γ-Linolenic Acid |
Gamolenic acid is an omega-6 fatty acid PPAR agonist found in vegetable oils. It is a precursor to prostaglandin E1 and eicsapentaenoic acid. It regulates insuilin secretion, inhibits diabetes mellitus-induced albuminuria, and induces apoptosis in leukemia cells. |
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DC33504 |
D-Luciferin Sodium
Featured
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D-Luciferin sodium is heterocyclic light-emitting compound and natural ligand for luciferase used to detect cell activity. It requires ATP for its reaction, emitting a greenish-yellow luminescence at a peak wavelength of approximately 530 nm. The salt form of luciferin dissolves in water or other typical buffers. |
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DC33505 |
NSC 21723 |
Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin. |
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DC33506 |
Keramamine A |
Manzamine A is a vacuolar ATPase uncoupler and GSK-3 inhibitor found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram positive and gram negative bacteria, and decreases tau hyperphosphorylation. |
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DC33507 |
Marbofloxacin
Featured
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Marbofloxacin is a bacterial DNA gyrase inhibitor. It suppresses growth of Staphylococus, Escherichia, Actinobacillus, Pasturella, and Mannhemia. |
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DC33508 |
1-Deoxy-1-(methylamino)-D-glucitol |
Meglumine is an amino sugar and sorbitol derivative used as a bulking agent in the formulation of pharmaceutical drugs. |
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DC33509 |
N 7001 |
Melitracen HCl ia potential dopamine D1/2 receptor antagonist used to treat depression. It is often co-administered with flupenthixol as a treatment for trigeminal neuralgia. It does not effect cardiovascular function. |
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DC33511 |
Preco |
S-Methoprene is a juvenile insect growth hormone analog that prohibits the ability of the insect to change from pupae to adult. It is used to control mosquito populations. It alters Ca 2+ signaling and redox activity of cytochrome oxidase and induces male sex differentiation. |
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DC33512 |
DL-alpha-Methylbenzyl isothiocyanate |
DL-alpha-Methylbenzyl isothiocyanate is an antioxidant that induces phase II enzyme activity. |
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