DC21454 |
P11
Featured
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PAFAH inhibitor P11 (P11) is a potent, selective platelet-activating factor acetylhydrolases PAFAH1b2 and PAFAH1b3 inhibitor with IC50 of 40 nM and 900 nM respectively. |
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DC10292 |
Pagoclone |
Pagoclone is an active (+)-enantiomer of the racemate RP 59037. Pagoclone is a partial GABA(A) receptor agonist used for the treatment of panic and anxiety disorders. |
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DC8717 |
PAK4-IN-1(KPT9274)
Featured
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PAK4-IN-1 is an inhibitor of p21-activated kinases (PAKs), with IC50 of ≤100 nM in MTT assay. |
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DC8469 |
Palbociclib
Featured
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Palbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. |
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DC5067 |
Palbociclib (PD0332991 HCl)
Featured
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Palbociclib is an oral, small molecule cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, now in Phase 3 clinical development for advanced breast cancer. |
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DC8470 |
Palbociclib isethionate
Featured
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Palbociclib isethionate(PD-0332991 isethionate) is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases. |
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DC7659 |
Palifosfamide
Featured
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Palifosfamide is a novel molecule for the treatment of sof tissue sarcoma. |
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DC9134 |
Paliperidone |
Paliperidone (9-hydroxyrisperidone) is a dopamine antagonist of the atypical antipsychotic class of medications. |
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DC10362 |
Palmitelaidic Acid |
Palmitelaidic acid is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue. |
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DC9897 |
Palmitoylethanolamide |
Palmitoylethanolamide(PEA) is an endogenous fatty acid amide and selectively activates PPAR-α in vitro with an EC50 value of 3.1±0.4 μM. |
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DC20491 |
Palmostatin B |
Palmostatin B is a potent Acyl protein thioesterase 1 (APT1. |
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DCAPI1448 |
PALONOSETRON HCL |
A serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is an antiemetic. |
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DC7970 |
ACT058362 (Palosuran)
Featured
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Palosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM. |
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DC8459 |
Palovarotene(R 667)
Featured
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Palovarotene (R-667, RO-3300074) is a selective retinoic acid receptor gamma(RAR-γ) agonist for the treatment of emphysema. |
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DC9681 |
Pamapimod(R-1503)
Featured
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Pamapimod(R-1503)is a novel p38 MAP kinase inhibitor. |
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DCAPI1259 |
Pamidronate Disodium |
Pamidronate Disodium |
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DCAPI1175 |
Pamidronic acid |
Pamidronic acid |
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DC20769 |
Pamiparib
Featured
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Pamiparib (BGB-290, BGB290) is a highly potent, selective and brain penetrant PARP1/2 inhibitor with potent anti-tumor activity. |
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DC4107 |
Panadiplon (U-78875) |
Panadiplon (U-78875) is an anxiolytic drug with a novel chemical structure that is not closely related to other drugs of this type. |
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DC20492 |
Pandacostat |
Pandacostat is the first nonselective HDAC inhibitor (pan-HDACi) with Ki of 0.12/0.07/0.95/0.18/0.032/1.1/0.5/1.4 uM for HDAC1/2/3/4/5/6/7/8/9, respectively. |
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DC7183 |
Panobinostat(LBH589)
Featured
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Panobinostat(LBH-589) is a broad-spectrum HDAC inhibitor; low nanomolar concentrations (IC50=5-20 nM) of LBH589 induced cell-cycle arrest, apoptosis, and histone (H3K9 and H4K8) hyperacetylation in MOLT-4 and Reh cell. |
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DC12642 |
pan-PIM inhibitor 17 |
pan-PIM inhibitor 17 is a potent, selective, orally available inhibitor of Pim kinase with IC50 of 0.8, 5.1 and 1.8 nM for Pim1, 2 and 3, respectively. |
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DC10199 |
Pan-RAS-IN-1 |
Pan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors. |
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DC9876 |
Pantoprazole |
Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
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DC9135 |
Pantoprazole Sodium |
Pantoprazole sodium salt(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
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DC12322 |
Papain |
Papain is a cysteine protease of the peptidase C1 family, which is used in food, pharmaceutical, textile, and cosmetic industries. |
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DC23618 |
PAPTP |
PAPTP is a PAP-1 derivative, potent, specific Kv1.3 channel inhibitor with IC50 of 31 nM in Jurkat T lymphocytes by patch-clamp, reduces cell viability and efficiently kills B16F10 cancer cells at 1 uM. |
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DC20234 |
PAQ
Featured
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PAQ (Compound 4c) is a quinoxaline derivative. PAQ is an orally active neuroprotective agent, which targets dopamine (DA) neurons and activates reticulum endoplasmic ryanodine receptor (RyR) channels, without effects on glia cells. |
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DC10875 |
Paquinimod
Featured
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Paquinimod is a S100A9 inhibitor, which prevents S100A9 binding to TLR-4. |
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DC9537 |
Paradol |
Paradol(6-Paradol) is the active flavor constituent of the seeds of Guinea pepper (Aframomum melegueta); Paradol has been found to have antioxidative and antitumor promoting effects.
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