| DCAPI1110 |
Oxibendazole |
Oxibendazole |
|
| DC8961 |
Potassium Oxonate |
Oxonic acid potassium salt is an inhibitor of uricase, oxonic inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and inta |
|
| DC10232 |
Oxybenzone |
Oxybenzone is a benzophenone derivative used as a sunscreen agent. |
|
| DC9112 |
Oxybutynin HCl |
Oxybutynin is also a possible treatment of hyperhidrosis (hyper-active sweating) . |
|
| DC20489 |
Oxythiamine chloride hydrochloride |
Oxythiamine chloride is a small molecule transketolase inhibitor with Kd of 33 nM, shows functional assay of human transketolase inhibition in HCT-116 cells with EC50 of 26 nM. |
|
| DC12352 |
Oxythiamine (Hydroxythiamin) |
Oxythiamine, an antimetabolite and a vitamin B1 antagonist, is a well-known thiamine antagonist and inhibitor of transketolase. |
|
| DCAPI1345 |
Ozagrel HCl |
Ozagrel HCl |
|
| DC9445 |
Ozagrel (sodium) |
Ozagrel(OKY-046) sodium salt is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.
|
|
| DC8281 |
Ozanimod (RPC1063)
Featured
|
Ozanimod (RPC1063) is a selective S1P1R modulator |
|
| DC7222 |
P005091(P5091)
Featured
|
P005091(P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM. |
|
| DC5188 |
Sarecycline(P005672 hydrochloride)
Featured
|
P005672 is a phase II drug for antibacterial/anti-inflammatory acne treatment. |
|
| DC11234 |
P053 |
P053 (P-053, CerS1 inhibitor P053) is a potent, selective, orally active inhibitor of ceramide synthase 1 (CerS1) with IC50 of 0.5 uM, displays >10-fold selectivity for inhibition of CerS2, CerS4, CerS5, and CerS6. |
|
| DC7221 |
P22077
Featured
|
P22077 is a potent inhibitor of ubiquitin-specific protease (USP) 7 (EC50=8.6 uM), P22077 also inhibits the closely related deubiquitinase (DUB) USP47. |
|
| DC20490 |
p32 inhibitor M36 |
p32 inhibitor M36 is a novel small molecule inhibitor of p32 mitochondrial protein, binds directly to p32 and inhibits p32 association with LyP-1. |
|
| DC23112 |
p38 MAPK-IN-4 |
p38 MAPK-IN-4 is a potent and selective inhibitor of p38 MAPK with IC50 of 68 nM for p38α, inhibits LPS-induced TNFα release in THP-1 cells with IC50 of 187 nM. |
|
| DC20001 |
p38α inhibitor 1 |
p38α inhibitor 1 is a p38α inhibitor extracted from patent WO 2008076265 A1. |
|
| DC10798 |
p38-α MAPK-IN-1
Featured
|
p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. |
|
| DC21934 |
P516-0475 |
P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM). |
|
| DC23317 |
P53R3 |
P53R3 is a novel p53 reactivator that restores sequence-specific DNA binding of the endogenously expressed p53(R175H) and p53(R273H) mutants in gel-shift assays. |
|
| DC21520 |
P62-mediated mitophagy inducer |
P62-mediated mitophagy inducer (PMI) is a small molecule P62-mediated mitophagy inducer that activates mitophagy without recruiting Parkin or collapsing membrane potential and retains activity in cells devoid of a fully functional PINK1/Parkin pathway. |
|
| DC7677 |
P7C3-A20
Featured
|
P7C3-A20 is an analogue of P7C3，a proneurogenic, neuroprotective agent. |
|
| DC7625 |
PA-824(Pretomanid)
Featured
|
PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2. |
|
| DC22060 |
PAC1 |
PAC1 (Compound PAC1) is a novel PROTAC antibody conjugate, more potent estrogen receptor-alpha (ERα) degrader compared to PROTAC without antibody conjugation.. |
|
| DC7477 |
pac-1
Featured
|
PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3. |
|
| DC10399 |
PAC-14028 |
PAC-14028 is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist. |
|
| DC12200 |
PACAP (6-38), human, ovine, rat TFA |
PACAP (6-38), human, ovine, rat is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively. |
|
| DC8638 |
Paclitaxel
Featured
|
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. |
|
| DC7478 |
Pacritinib |
Pacritinib (SB1518) is a potent and selective JAK2 (IC50 = 23 and 19 nM for JAK2WT and JAK2V617F, respectively) and FLT3 (IC(50) = 22 nM) inhibitor with selectivity against JAK1 and JAK3 (IC50= 1280 and 520 nM, respectively). |
|
| DC21408 |
Pactamycin |
Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial act |
|
| DC11113 |
Padsevonil |
Padsevonil (UCB-0942, UCB0942) is a potential anti-seizure agent that functions as a pre- and post-synaptic inhibitor.. |
|
