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Cat. No. Product Name Field of Application Chemical Structure
DC9979 PRX-08066 Featured PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that causes selective vasodilation of pulmonary arteries.
DC21536 PS210 Featured PS 210 is a potent, specific activator of PDK1 that target the PIF-binding pocket of PDK1, does not alter the activity of any of the 121 kinases (S6K, PKB/Akt or GSK3)..
DC21537 PS 423 PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210.
DC23286 PS1 PS1 is a potent inhibitor of IAP family with IC50 of 36/96/33 nM for c-IAP1/c-IAP2/XIAP respectively..
DC21468 PS10 PS10 (PDK inhibitor PS10) is a novel potent and highly selective pyruvate dehydrogenase kinase (PDK) inhibitor.
DC7969 PS-1145 Featured PS-1145 has been shown to be an IKK (IKB kinase) inhibitor.
DC23838 PS-432 PS-432 is an allosteric inhibitor of PKCι and PKCζ with IC50 of 16.9 and 18.5 uM, respectively.
DC22313 PS48 Featured PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site.
DC21538 PSB-12379 disodium PSB-12379 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.03/2.21 nM for rat/human recombinant eN.
DC21539 PSB-12431 PSB-12431 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.2 nM for rat recombinant eN.
DC21540 PSB-12553 PSB-12553 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.5 nM for rat recombinant eN.
DCAPI1432 Mupirocin Pseudomonic Acid, also known as mupirocin, is an antibiotic isolated from Pseudomonas fluorescens which strongly inhibits protein and RNA synthesis. Inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit isole
DC4121 PSI6130 Featured PSI-6130(R 1656) is a Hepatitis C Virus Nucleoside Inhibitor. PSI-6130(R 1656) is useful for Antiviral agents.
DC6309 PSI6206 Featured PSI-6206 is a selective inhibitor of hepatitis C virus (HCV).
DC10162 PSI-7409 PSI-7409 is the active 5′-triphosphate metabolite of PSI-7851. PSI-7851 is a selective and highly active nucleotide analog inhibitor of HCV.
DC6308 Sofosbuvir(PSI7977,GS-7977) Featured PSI-7977 is an investigational nucleotide analog currently in Phase 2 for treatment of chronic HCV infection.
DC12162 PSMA-617 Featured PSMA-617 is a high potent prostate-specific membrane antigen (PSMA) inhibitor, with a Ki of 0.37 nM.
DC7893 PSN632408 PSN632408 is an optimized agonist of GPR119 receptors that shows similar potency to OEA at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 5.6 and 7.9 uM, respectively.
DC23683 PSN-GK1 PSN-GK1 is a potent, orally available Glucokinase (GK) activator with EC50 of 130 nM at 5 mM glucose (4.3-fold).
DC23654 Psora-4 Featured Psora-4 is a potent and selective Kv1.3 potassium channel blocker with EC50 of 3 nM.
DC23199 Psoralidin Featured Psoralidin possesses potent antidepressant-like, anti-inflammatory, anticancer and chemopreventive properties. Psoralidin is a dual inhibitor of COX-2 and 5-LOX
DC20513 PST-1 PST-1 is a photoswitchable inhibitor of microtubule with EC50 of 0.5 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.
DC20514 PST-1P PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.
DC10464 PT2385 Featured PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential antineoplastic activity.
DC9811 PT2399 Featured PT2399(PT=2399) is a novel HIF2α Antagonist.
DC8654 PTACH (NCH-51) Featured PTACH (NCH-51) is a SAHA-based novel inhibitor of human HDAC. PTACH exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1 to 10 μM.
DC7552 PTC-028 Featured PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification
DC2005 PTC124 (Ataluren) Featured PTC124 (Ataluren) is a potent nonsense mutation inhibitor with EC50 of ~0.1 μM.
DC7485 PTC-209 Featured PTC-209 is a specific inhibitor for BMI-1 with IC50 of 0.5 uM in in both GEMS reporter and ELISA assays.
DC8495 PTC-209 hydrobromide Featured PTC-209 is a specific inhibitor for BMI-1 with IC50 of 0.5 uM in in both GEMS reporter and ELISA assays.

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