DC Chemicals' products qualify for U.S. tariff exemptions. We guarantee no price increases due to customs duties and maintain stable supply, continuing to deliver reliable research solutions to our American clients.
| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC12482 | PTC299 Featured | PTC299 (PTC-299) is a novel potent inhibitor of dihydroorotate dehydrogenase (DHODH), inhibits hypoxia-induced VEGFA protein production in HeLa cells with IC50 of 1.64 nM. |
|
| DC21543 | PTC725 | PTC725 is a potent, selective, and orally bioavailable inhibitor of HCV NS4B, inhibits HCV 1b (Con1) replicons with EC50 of 1.7 nM. |
|
| DC20592 | Pterosin B | Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain. |
|
| DC20516 | PTGR2-IN-22 | PTGR2-IN-22 is a potent PTGR2 ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells. |
|
| DC10333 | PTP1B-IN-2 Featured | PTP1B-IN-2 is a novel protein tyrosine phosphatase-1B (PTP1B) inhibitor. |
|
| DC20517 | PTP1B-IN-5b | PTP1B-IN-5b is a potent protein tyrosine phosphatase PTP1B inhibitor with IC50 of 5.25 uM. |
|
| DC20518 | PTUPB | PTUPB is a novel dual acting COX-2/sEH inhibitor with IC50 of 1.26 uM/0.9 nM,does not inhibits COX-1 (IC50>100 uM). |
|
| DC8129 | PTZ-343 Featured | PTZ-343 is a phenothiazine derivative with chemical name: sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. |
|
| DC23354 | PU-139 | PU-139 is a potent, unselective HAT (Histone acetyltransferase) inhibitor that blocks the HATs Gcn5, p300/CBP-associated factor (PCAF), CREB protein (CBP) and p300. |
|
| DC23363 | PU-141 | PU-141 is a potent, selective CBP/p300 inhibitor that inhibits SK-N-SH cell growth with GI50 of 0.48 uM. |
|
| DC9919 | Pulchinenoside A | Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice. |
|
| DC9911 | Pulsatilla saponin D（SB365） | Pulsatilla saponin D(SB365) isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer. |
|
| DC23274 | Purfalcamine Featured | Purfalcamine is a potent, specific inhibitor of Plaasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) with IC50 of 17 nM. |
|
| DCZ-287 | Protopine | purity >98%,Standard References |
|
| DCZ-284 | Allosecurinine | Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from Phyllanthus glaucus . |
|
| DCZ-291 | isorhapontigenin | purity >98%,Standard References |
|
| DCZ-292 | TECTOCHRYSIN | purity >98%,Standard References |
|
| DCZ-290 | Isobavachin | purity >98%,Standard References |
|
| DCZ-286 | 8-GERANOPSORALEN | purity >98%,Standard References |
|
| DCZ-289 | songorine | purity >98%,Standard References |
|
| DC7255 | Purmorphamine Featured | Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM. |
|
| DC8558 | Puromycin aminonucleoside Featured | Puromycin Aminonucleoside (3'-Amino-3'-deoxy-N6,N6-dimethyladenosine) is the aminonucleoside portion of the antibiotic puromycin. |
|
| DC10169 | Puromycin Featured | Puromycin is an aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. It is a protein synthesis inhibitor. |
|
| DC8075 | Purvalanol A(NG 60) Featured | Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. |
|
| DC7256 | Purvalanol B(NG-95) Featured | Purvalanol B(NG-95) is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. |
|
| DC23344 | PVZB-1194 | PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM. |
|
| DC26129 | PWT143 (ME-401) Featured | PWT143 (ME-401), is an orally bioavailable inhibitor of the delta isoform of phosphatidylinositide 3-kinase (PI3K), with potential antineoplastic activity. |
|
| DC23657 | PWZ-029 | PWZ-029 is a potent, subtype-selective partial inverse agonist of α5 GABAA receptors with Ki of 30 nM, demonstrates memory enhancing effects in vivo. |
|
| DC20222 | Px-104 | Px-104(Px-102) is a farnesoid X receptor (FXR) agonist potentially for the treatment of non-alcoholic fatty liver disease. |
|
| DC7992 | PX 12 Featured | PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1(Trx-1) currently in clinical development as an antitumor agent; IC50=7 uM in Hela, MTT assay, 72 h. |
|
