Cat. No. | Product name | CAS No. |
DC8177 |
Enclomiphene citrate
Featured
Enclomiphene is a non-steroidal estrogen receptor antagonist that promotes gonadotropin-dependent testosterone secretion by the testes. |
7599-79-3 |
DC8265 |
Endoxifen
Featured
Endoxifen is a Estrogen receptor α (ERα) ligand; potent antiestrogen,an active metabolite of the cancer drug tamoxifen. |
112093-28-4 |
DC6909 |
Entinostat (MS-275)
Featured
Entinostat (MS-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, compared with HDACs 4, 6, 8, and 10. Phase 1/2. |
209783-80-2 |
DC8300 |
Entrectinib (RXDX-101)
Featured
Entrectinib (RXDX-101), a potent and selective small molecule inhibitor of TrkA/B/C, ROS1, and ALK kinases, has demonstrated early clinical activity when orally administered intermittently under fasting conditions. |
1108743-60-7 |
DC5057 |
Enzastaurin (LY317615)
Featured
Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3. |
170364-57-5 |
DCAPI1356 |
Epalrestat
Featured
Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy. |
82159-09-9 |
DC11433 |
Vatiquinone
EPI-743 (Vatiquinone,EPI-589) is an orally bioavailable para-benzoquinone for treatment of inherited mitochondrial diseases, an analogue of the antioxidant ubidecarenone. |
1213269-98-7 |
DC9260 |
Eptapirone
Featured
Eptapirone (F-11,440) is a very potent and highly selective 5-HT1A receptor full agonist of the azapirone family. |
179756-58-2 |
DC7927 |
EPZ011989
Featured
EPZ011989 is a potent, orally-available EZH2 Inhibitor. |
1598383-40-4 |
DC11387 |
Erdafitinib
Featured
Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1-4 with IC50 values of 1.2, 2.5, 3.0 and 5.7nM, respectively. |
1346242-81-6 |
DCAPI1539 |
Eribulin Mesylate
Featured
Eribulin is an anticancer drug marketed by Eisai Co. under the trade name Halaven. Eribulin is also known as E7389 and ER-086526, and also carries the US NCI designation NSC-707389. It is used to treat certain patients with breast cancer and liposarcoma. |
441045-17-6 |
DCAPI1516 |
Eribulin
Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules. |
253128-41-5 |
DC2101 |
Erlotinib free base
Featured
Erlotinib (OSI-744; NSC 718781; R1415) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. |
183321-74-6 |
DC3139 |
Erlotinib hydrochloride
Featured
Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM. |
183319-69-9 |
DC8182 |
Bempedoic Acid(ETC-1002;ESP-55016)
Featured
ETC-1002(ESP-55016) is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM). |
738606-46-7 |
DC8489 |
ETC-159
Featured
ETC-159 is a potent and specific inhibitor of Wnt secretion. ETC-159 inhibits _beta_-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9 nM. |
1638250-96-0 |
DCAPI1535 |
Etodolac
Etodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of ab |
41340-25-4 |
DC10040 |
Etrasimod(APD334)
Featured
Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1(S1P1) receptor with an IC50 value of 1.88 nM in CHO cells. |
1206123-37-6 |
DC4234 |
Etravirine
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1). |
269055-15-4 |
DC7125 |
Evacetrapib (LY2484595)
Featured
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. |
1186486-62-3 |
DC1501 |
Everolimus
Featured
Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM. |
159351-69-6 |
DC10380 |
Evobrutinib
Featured
Evobrutinib is an inhibitor of Bruton's tyrosin kinase (Btk) inhibitor extracted from patent US20140162983 example 0174. |
1415823-73-2 |