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AC-55649

  Cat. No.:  DC12086   Featured
Chemical Structure
59662-49-6
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More than 5000 active chemicals with high quality for research!
Field of application
AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 59662-49-6
Chemical Name: [1,1'-Biphenyl]-4-carboxylicacid, 4'-octyl-
Synonyms: [1,1'-Biphenyl]-4-carboxylicacid, 4'-octyl-;4-(4-octylphenyl)benzoic acid;4-Octyl-4'-biphenylcarboxylic acid;4-OCTYLBIPHENYL ACID;AC 55649;4-n-octylbiphenyl-4'-carboxylic acid;4'-octyl-4-phenylbenzoic acid;4'-Octylbiphenyl-4-carboxylic acid;4'-octyloxy-4-biphenylcarboxylic acid;8BCA;octyldiphenylcarboxylic acid;4′-Octyl-4-biphenylcarboxylic acid, 4′-n-octylbiphenyl-4-carboxylic acid;AC-55649
SMILES: CCCCCCCCC1=CC=C(C=C1)C2=CC=C(C(O)=O)C=C2
Formula: C21H26O2
M.Wt: 310.42994
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.
Target: RARβ2:6.9 (pEC50)
In Vitro: AC-55649 is a potent, highly isoform-selective agonist at the human RARβ2 receptor, with a pEC50 of 6.9[1]. AC-55649 is a potent and selective activator of RARβ2 transcriptional activity[2].
References: [1]. Lund BW, et al. Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J Med Chem. 2005 Dec 1;48(24):7517-9. [2]. Piu F, et al. Identification of novel subtype selective RAR agonists. Biochem Pharmacol. 2005 Dec 19;71(1-2):156-62.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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