| DC47758 |
Aβ Fibrillization modulator 1
|
Aβ Fibrillization modulator 1 stabilizes Aβ monomers. |
| DC46940 |
AZD4694
|
AZD4694, a fluorinated β-amyloid (Aβ) plaque neuroimaging PET radioligand, shows high affinity for Aβ fibrils (Kd = 2.3 nM). |
| DC46641 |
Methyl tridecanoate
|
Methyl tridecanoate moderately inhibits β-amyloid aggregation. Methyl tridecanoate weakly inhibits acetylcholinesterase (AChE). |
| DC45833 |
Aβ/tau aggregation-IN-1
|
Aβ/tau aggregation-IN-1 is a potent Aβ1-42 β-sheets formation and tau aggregation inhibitor. The KD values of Aβ/tau aggregation-IN-1 with Aβ1-42 and tau are 160 μM and 337 μM, respectively. Aβ/tau aggregation-IN-1 can permeate the blood-brain barrier. |
| DC45771 |
RAGE antagonist peptide TFA
|
RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA possesses anti-tumor and anti-inflammatory activities. |
| DC44797 |
Cl-NQTrp
|
Cl-NQTrp signifcantly disrupts the preformed fbrillar aggregates of Tau-derived PHF6 (VQIVYK) peptide and full-length tau protein. |
| DC44796 |
Beta-Amyloid(1-14),mouse,rat
|
Beta-Amyloid(1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. |
| DC44795 |
β-Amyloid (22-40)
|
β-Amyloid (22-40) is a peptide fragment of β-Amyloid. |
| DC44794 |
β-Amyloid (11-22)
|
β-Amyloid (11-22) is a peptide fragment of β-Amyloid. |
| DC44520 |
Ezeprogind
|
Ezeprogind (AZP-2006) is an orally active neurotrophic inducer. Ezeprogind targets all causes of neurodegeneration and is not only aiming at markers such as Abeta protein or tau protein. Ezeprogind is a potent neuroprotectant and can be used for the research of neurological disorders, including progressive supranuclear palsy (PSP), tauopathies, alzheimer’s and parkinson’s diseases, et al. |
