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DL-AP7

  Cat. No.:  DC9250   Featured
Chemical Structure
85797-13-3
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More than 5000 active chemicals with high quality for research!
Field of application
DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 85797-13-3
Chemical Name: ( /-)-2-AMINO-7-PHOSPHONOHEPTANOIC
Synonyms: ( /-)-2-AMINO-7-PHOSPHONOHEPTANOIC;(+ -)-2-AMINO-7-PHOSPHONO-HEPTANOIC ACID
SMILES: NC(CCCCCP(O)(O)=O)C(O)=O
Formula: C7H16NO5P
M.Wt: 225.17944
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1].
In Vitro: DL-AP7 (ICV) blocks the NMDA-induced convulsions (ED50=0.22 nmol/mouse) and impairs learning performance in a passive avoidance task in mice[1].
References: [1]. Chiamulera C, et al. Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology (Berl). 1990;102(4):551-552.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
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DC7989 PEPA PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
DC11382 NYX-2925 NYX-2925 is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory.
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DC7194 MDL 29951 MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.
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