IDO-IN-2|cas 1668565-74-9|DC Chemicals

Cas No.:	1668565-74-9
Chemical Name:	Ido-IN2
Synonyms:	IDO-IN-2;IDO-IN2;1-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-3-(4-methylphenyl)urea;Urea, N-[4-[bis(2-methylpropyl)amino]-2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]-N'-(4-methylphenyl)-;AMY16308;BCP20804;BDBM50454785;AK685633;S8557;1-(4-(Diisobutylamino)-2'-(1H-tetrazol-5-yl)biphenyl-3-yl)-3-p-tolylurea;PCC0208009
SMILES:	O=C(N([H])C1C([H])=C([H])C(C([H])([H])[H])=C([H])C=1[H])N([H])C1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2C2N=NN([H])N=2)C([H])=C([H])C=1N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
Formula:	C₂₉H₃₅N₇O
M.Wt:	497.6345
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC10022	PF06840003	PF-06840003 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1),with potential immunomodulating and antineoplastic activities.
DC8021	Indoximod (NLG-8189)	NLG-8189 is an inhibitor of IDO and INDOL1 (IDO2)
DC7015	INCB024360 analogue(IDO-IN-1)	INCB024360 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical properties, which is poised to start clinical trials in cancer patients.
DC10421	IDO-IN-2	IDO-IN-2 is an IDO inhibitor extracted from patent WO/2015031295 A1, compound example 1, has IC50 values of 0.068 μM in HeLa cell and 0.16 μM in HEK293 cell.
DC10098	IDO-IN-1	IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM).
DC8389	Epacadostat (INCB024360)	Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM. Phase 2.
DC10131	BMS-986205(Linrodostat)	BMS-986205 is an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic activity, alone and in combination with nivolumab in advanced cancers in a phase 1/2a trial