Isoxazole 9(ISX9)

  Cat. No.:  DC8304   Featured
Chemical Structure
832115-62-5
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More than 5000 active chemicals with high quality for research!
Field of application
ISX-9 is a small molecule inducer of adult neural stem cell differentiation both in vitro and in vivo.
Cas No.: 832115-62-5
Chemical Name: N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide
Synonyms: N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide;Isoxazole 9;ISX 9;ISX-9;N-Cyclopropyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide
SMILES: O=C(C1=NOC(C2=CC=CS2)=C1)NC3CC3
Formula: C11H10N2O2S
M.Wt: 234.2743
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 μM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC8304 Isoxazole 9(ISX9) ISX-9 is a small molecule inducer of adult neural stem cell differentiation both in vitro and in vivo.
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