Cobalt protoporphyrin IX chloride

  Cat. No.:  DC70317  
Chemical Structure
102601-60-5
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Field of application
Cobalt protoporphyrin IX (CoPPIX) is a potent and effective inducer of HO-1 (heme oxygenase-1) activity, up-regulates HO-1 via Bach1 and Nrf2 in human liver cells.CoPPIX did not influence hepatic Bach1 or Nrf2 mRNA levels, but markedly reduced Bach1 protein levels by increasing degradation of Bach1 protein, and increased Nrf2 by decreasing degradation of Nrf2 protein.CoPPIX significantly upregulated HO-1 protein in mucosal and submucosal cells.CoPPIX is a direct Bach1 inhibitor.
Cas No.: 102601-60-5
Chemical Name: Cobalt protoporphyrin IX chloride
Synonyms: CoPPIX, CoPP
Formula: C34H30ClCoN4O4.2H
M.Wt: 655.03
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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