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QS-7

  Cat. No.:  DC67236   Featured
Chemical Structure
208933-54-4
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More than 5000 active chemicals with high quality for research!
Field of application
QS 7 (QS 7 Api) is a saponin compound that can be extracted from the Quillaja saponaria tree. QS 7 activates immune cells, enhances their antigen presentation ability and cytokine secretion. QS 7 can be used as vaccine adjuvant for immunostimulating, anti-tumor, and anti-infectious activities.
Cas No.: 208933-54-4
Chemical Name: Quillaja saponin 7
Synonyms: β-D-Glucopyranosiduronic acid, (3β,4α,16α)-28-[(O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-[β-D-glucopyranosyl-(1→3)]-O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-4-O-acetyl-6-deoxy-β-D-galactopyranosyl)oxy]-16-hydroxy-23,28-dioxoolean-12-en-3-yl O-β-D-galact...;Quillaja saponaria saponin 7;QS-1862;QS 7 Api;QS 7;QS 1862;NP 017705
SMILES: [C@H]1(O)[C@@H](O)[C@@H](CO)O[C@@]([C@@H]1O)([H])O[C@@H]1[C@H]([C@H](O)[C@H](O[C@@]1([H])O[C@H]1CC[C@]2([C@@]([H])(CC[C@]3(C)[C@]2([H])CC=C2[C@@]3(C)C[C@@H](O)[C@@]3([C@@]2([H])CC(C)(CC3)C)C(O[C@@H]2O[C@H](C)[C@H](OC(=O)C)[C@H](O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@H]2O[C@@]2([H])[C@H](O)[C@H](O[C@@]3([H])[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)[C@@H](O[C@]3([H])OC[C@@H](O)[C@H](O[C@]4([H])OC[C@](O)(CO)[C@H]4O)[C@H]3O)[C@H](C)O2)=O)[C@@]1(C=O)C)C)C(O)=O)O[C@@]1([H])[C@@H]([C@@H](O)[C@H](O)CO1)O
Formula: C83H130O46
M.Wt: 1863.89
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
DC67240 KRN-7000(7DW8-5)
DC67239 KRN-7000(S34)
DC67238 KRN-7000(C34)
DC67237 TQL-1055 TQL-1055 is a semi-synthetic analog of the saponin adjuvant QS-21 (HY-101092) and can be used as a prophylactic vaccine adjuvant. TQL-1055 exhibits robust adjuvant activity for influenza antigens. TQL-1055 combined with the acellular pertussis vaccine (aP) shows good tolerance and enhances the antibody response to pertussis toxin (PT) in mice and rabbits. TQL-1055 is promising for research of chronic hepatitis B.
DC67236 QS-7 QS 7 (QS 7 Api) is a saponin compound that can be extracted from the Quillaja saponaria tree. QS 7 activates immune cells, enhances their antigen presentation ability and cytokine secretion. QS 7 can be used as vaccine adjuvant for immunostimulating, anti-tumor, and anti-infectious activities.
DC67235 CPG 7909
DC67233 AYK004-C1 AYK004-C1 is a TLR agonist. AYK004-C1 can be used to prepare immune adjuvants.
DC67232 AYK004-B1 AYK004-B1 is a TLR7 agonist (EC50=0.2265 nM). AYK004-B1 can be used to prepare immune adjuvants.
DC67231 AYK004 AYK004 is a TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. AYK004 is an adenine derivative with a favorable hydrophilic-lipophilic balance, which improves the loading capacity and stability in immunoadjuvant systems such as liposomes, while reducing the side effects of the immunoadjuvant system in systemic immunity .
DC67230 AYK005 AYK005 is a TLR7/8 immunologic adjuvant.
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