Cat. No. | Product name | CAS No. |
DC23053 |
Isosilybin
Featured
Isosilybin is a flavanolignan found in the extract of S. marianum fruits with antioxidant and anticancer activities.It inhibits lipid peroxidation in rat liver microsomes (IC50 = 32 μM) and reduces ADP/Fe3+-induced malondialdehyde (MDA) production and lac |
72581-71-6 |
DC9824 |
Isosteviol
Featured
Isosteviol is a derivative of stevioside, a constituent of Stevia rebaudiana, which is commonly used as a noncaloric sugar substitute in Japan and Brazil. |
27975-19-5 |
DC23095 |
ISOVITEXIN
Featured
Isovitexin, a food phytochemical contained in dietary rice products, it exhibits in vivo α-glucosidase inhibition, it possesses antihyperglycemic, neuroprotective, anti-inflammatory and anti-oxidant activities. Isovitexin inhibited xanthine oxidase with a |
38953-85-4 |
DC5107 |
SB-715992 (Ispinesib)
Featured
Ispinesib (SB 715992) is a potent mitotic kinesin KSP (Eg5) inhibitor with a Ki and an IC50 of 0.6 and 4.1 nM, respectively. |
336113-53-2 |
DC7431 |
ISRIB
Featured
ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM. |
1597403-47-8 |
DC22333 |
iST2-2
Featured
iST2-2 is a novel ST2 (suppression of tumorigenicity 2) inhibitor active in vivo. |
|
DCAPI1080 |
Istradefylline (KW-6002)
Featured
Istradefylline(KW6002) is a very potent, selective and orally active adenosine A2A receptor antagonist(Ki=2.2 nM) in experimental models of Parkinson's disease. |
155270-99-8 |
DC8304 |
Isoxazole 9(ISX9)
Featured
ISX-9 is a small molecule inducer of adult neural stem cell differentiation both in vitro and in vivo. |
832115-62-5 |
DC10898 |
Protein kinase inhibitor 1
Featured
It is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. |
1365986-44-2 |
DC10768 |
IT 901
Featured
IT 901 is a c-Rel inhibitor (IC50 = 3 μM). Inhibits IL-2 expression in activated T-cells in vitro. |
1584121-99-2 |
DC10283 |
IT1t dihydrochloride
Featured
IT1t dihydrochloride is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. |
1092776-63-0 |
DC12378 |
Itacitinib(INCB039110)
Featured
Itacitinib is a potent and selective inhibitor of JAK1, with >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2; Itacitinib is used in the research of myelofibrosis. |
1334298-90-6 |
DC8028 |
ITD-1
Featured
ITD-1 is a novel and highly selective TGFβ pathway inhibitor. ITD-1 molecule turns stem cells into heart cells. |
1099644-42-4 |
DC23662 |
ITI214 free base
Featured
ITI-214 is a potent, selective phosphodiesterase 1 (PDE1) inhibitor with Ki of 58 pM, displays >1,000-fold selectivity over PDE4A/4D and other PDE isoforms. |
1160521-50-5 |
DC10220 |
ITSA-1 (ITSA1)
Featured
ITSA-1 (ITSA1) is an HDAC activator via TSA suppression, but shows no activity towards other HDAC inhibitors. |
200626-61-5 |
DC21157 |
ITX-5061 hydrochloride
Featured
ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels. |
1252679-52-9 |
DC26005 |
IU1
Featured
IU1 is a selective USP14 inhibitor. IU1 prevents ventilator-induced lung injury in rats. |
314245-33-5 |
DC23797 |
IU1-47
Featured
IU1-47 is a potent, selective small-molecule inhibitor of USP14 with IC50 of 0.6 uM, shows 10-fold more potent over IU1 and retains specificity for USP14; accelerates the rate of degradation of wild-type tau, the pathological tau mutants P301L and P301S, and the A152T tau variant in primary neuronal cultures, a specific residue in tau, lysine 174, is critical for the IU1-47-mediated tau degradation by the proteasome; stimulates autophagic flux in primary neurons. |
670270-31-2 |
DC3153 |
Ivabradine hydrochloride
Featured
Ivabradine, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent. |
148849-67-6 |
DC4128 |
Ivacaftor (VX-770)
Featured
Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. |
873054-44-5 |
DC7434 |
IWP-L6
Featured
IWP L6 is a Porcn inhibitor with EC50 of 0.5 nM. |
1427782-89-5 |
DC5028 |
IWP-2
Featured
IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. |
686770-61-6 |