Cat. No. | Product name | CAS No. |
DC7175 |
JNJ-26854165 (Serdemetan)
Featured
JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. |
881202-45-5 |
DC23567 |
JNJ303
Featured
JNJ303 is a potent, specific delayed rectifier potassium current I(Ks) blocker with IC50 of 64 nM, shows no effects on other cardiac channels (IC50=3.3, >10, 11.1 and 12.6 uM for Na, ICa, Ito and IKr currents). |
878489-28-2 |
DC8140 |
JNJ31020028
Featured
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22 rat); >100-fold selective versus human Y1/Y4/Y5 receptors. |
1094873-14-9 |
DC7177 |
JNJ 38877605
Featured
JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. |
943540-75-8 |
DC8617 |
JNJ-42041935
Featured
JNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes. |
1193383-09-3 |
DC9662 |
JNJ-42165279
Featured
JNJ-42165279 is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC50 of 70nM. |
1346528-50-4 |
DC22125 |
JNJ4796
Featured
JNJ4796 (JNJ 4796, JNJ-4796) is an orally active small-molecule fusion inhibitor of influenza virus hemagglutinin (HA) with EC50 of 33 nM (H1N1 neutralization). |
2241664-16-2 |
DC21180 |
JNJ-47965567
Featured
JNJ-47965567 is a potent, selective, centrally permeable P2X7 receptor antagonist with pKi of 7.9 and 8.7 for human and rat P2X7, respectively. |
1428327-31-4 |
DC12166 |
JNJ-5207852
Featured
JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively. |
398473-34-2 |
DC21182 |
JNJ-53718678
Featured
JNJ-53718678 (JNJ53718678, JNJ-678) is a potent (Kd=7.4 nM), small-molecule inhibitor of the F-glycoprotein-mediated complex membrane fusion process of the RSV. |
1383450-81-4 |
DC12271 |
JNJ-54175446
Featured
JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively. |
1627902-21-9 |
DC10882 |
JNJ-632
Featured
JNJ-632 is a novel and potent inhibitor of HBV replication in vitro across genotypes A-D. |
1572510-42-9 |
DC9271 |
JNJ-63533054
Featured
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM. |
1802326-66-4 |
DC7178 |
JNJ-7706621
Featured
JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6; also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1. |
443797-96-4 |
DC8773 |
JNJ-7777120
Featured
JNJ-7777120 is a selective H4R antagonist with Ki of 4 ±1 nM, exhibits >1000-fold selectivity over the other histamin receptors. |
459168-41-3 |
DC22516 |
Unii-cedo9qxyzk
Featured
JPH203 (KYT-0353) is a potent, selective L-type amino acid transporter 1 (LAT1, SLC7A5) inhibitor with IC50 of 60 nM (leucine uptake inhibition), but not LAT2. |
1037592-40-7 |
DC12191 |
JQ-35-(S)
Featured
JQ-35, (S)- is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins with potential antineoplastic activity. |
1349719-98-7 |
DC11421 |
JQEZ5
Featured
JQEZ5 is a novel and potent EZH2 inhibitor. |
1913252-04-6 |
DC12422 |
JSH-150
Featured
JSH-150 (JSH150) is a potent, highly selective inhibitor of CDK9 kinase with IC50 of 1 nM in the biochemical assays, displays 300-10000-fold selectivity over other CDK kinase family members (CDK7 IC50=1.72 uM). |
2247481-21-4 |
DC7741 |
JSH-23
Featured
JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM. |
749886-87-1 |
DC10607 |
JTE-013
Featured
JTE 013 is a potent and selective S1P2 antagonist with IC50 of 17.6 nM. |
383150-41-2 |
DC26081 |
JTE-852
Featured
JTE-852 is a novel potent, selective, ATP-competitive Syk kinase inhibitor with IC50 of 1.25/1.28 nM for human/rat Syk, respectively. |
909283-40-5 |