Cat. No. | Product name | CAS No. |
DC22143 |
MALAT1-IN-1
Featured
MALAT1 inhibitor 5 (Malat1 inhibitor 5) is a selective small molecule targeting of Metastasis-associated lung adenocarcinoma transcript 1 (Malat1/MALAT1 mouse/human), a highly conserved long non-coding RNA; does not affect Neat1 lncRNA levels. |
827327-28-6 |
DC12536 |
Malic Enzyme inhibitor ME1
Featured
Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM, suppresses growth of human CRC cells in vitro, with little effect on normal rat intestinal epithelial cells.. |
522649-59-8 |
DC20141 |
Maltitol
Featured
Maltitol is a sugar alcohol used as a sugar substitute. It has 75-90% of the sweetness of sucrose (table sugar) and nearly identical properties. Maltitol may also be used as a plasticizer in gelatin capsules, as an emollient, and as a humectant. |
585-88-6 |
DC23814 |
MAP4K4-IN-17
Featured
MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933. |
1811510-58-3 |
DC4217 |
Maraviroc
Featured
Maraviroc (Selzentry, UK-427857, Celsentri) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively. |
376348-65-1 |
DC8909 |
Maribavir
Featured
Maribavir(GW257406X; BW1263W94; 1263W94) inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97. |
176161-24-3 |
DC22297 |
Marmesin
Featured
Marmesin is a coumarin originally isolated from the mature bark of A. marmelos. |
13849-08-6 |
DC7460 |
Masitinib
Featured
Masitinib is a broad coronavirus 3CL inhibitor that effectively blocks replication of SARS-CoV-2. Science 20 Jul 2021: eabg5827 DOI: 10.1126/science.abg5827 |
790299-79-5 |
DC11524 |
Mavacamten(MYK-461)
Featured
Mavacamten(MYK-461)is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain. |
1642288-47-8 |
DC8378 |
Mavatrep(JNJ-39439335)
Featured
Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6. |
956274-94-5 |
DC7681 |
Mavoglurant (AFQ 056)
Featured
Mavoglurant (AFQ056) is an experimental drug candidate for the treatment of fragile X syndrome.It exerts its effect as an antagonist of the metabotropic glutamate receptor 5 (mGLU5). |
543906-09-8 |
DC11285 |
MAZ51
Featured
MAZ51 is an indolinone that selectively antagonizes the activation of VEGFR3 by VEGFC (IC50 = 1 µM) without blocking VEGFC-mediated stimulation of VEGFR2. |
163655-37-6 |
DC11236 |
MB-07811 (VK-2809)
Featured
MB-07811 (VK-2809) is an orally bioavailable, liver-targeted prodrug of MB07344, which is a thyroid hormone receptor-beta agonist (TRβ) agonist, efficiently converted to MB07344 by liver microsomes in vivo. |
852948-13-1 |
DC10957 |
MB725
Featured
MB725 is a small-molecule p53 mutant Y220C stabilizer, induces selective viability reduction in several p53-Y220C cancer cell lines (Huh7 cell IC50=10 uM). |
2230058-99-6 |
DC10062 |
MBP146-78
Featured
MBP146-78 inhibits the growth of Eimeria spp. both in vitro and in vivo. |
188343-77-3 |
DC7193 |
MBX-2982
Featured
MBX-2982 is a selective, orally-available GPR119 agonist for the treatment of type 2 tiabetes. |
1037792-44-1 |
DC10872 |
MBX-4132
Featured
MBX-4132 a trans translation inhibitor by binding to the bacterial ribosome. |
2286411-30-9 |
DC5128 |
MC1568
Featured
MC1568 is a class II (IIa) HDAC inhibitor selective for HDAC4 and HDAC6 |
852475-26-4 |
DC12527 |
MC180295
Featured
MC180295 (MC-180295, MC 180295) is a novel potent, highly selective CDK9 inhibitor with IC50 of 5 nM, displays >22-fold selectivity over other CDKs. |
2237942-08-2 |
DC10940 |
MC3343
Featured
MC3343 (MC-3343) is a novel potent, non-nucleoside DNA methyltransferase (DNMT) inhibitor with IC50 of 5.7 and 1.7 uM for DNMT1 and DNMT3a. |
1535187-91-7 |
DC11338 |
MMP-2/MMP-7 Fluorogenic Substrate Control
Featured
Mca-PL is a fluorogenic peptide that has been used as a building block in the synthesis of Mca-PLGL-Dpa-AR-NH2, a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. |
140430-55-3 |
DC8550 |
MCB-613
Featured
MCB-613 is a novel and potent stimulator of p160 steroid receptor coactivators (SRCs). It is a Pan-SRCs stimulator. |
1162656-22-5 |