Cat. No. | Product name | CAS No. |
DC8226 |
RI-2
Featured
RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells. |
1417162-36-7 |
DCAPI1165 |
Ribavirin (Copegus)
Featured
Ribavirin is a guanosine analog with antiviral properties against DNA and RNA viruses, including respiratory syncytial virus, hepatitis C, and influenza. |
36791-04-5 |
DC24015 |
Ribocil
Featured
Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB. |
1381289-58-2 |
DC7265 |
Rigosertib
Featured
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM; shows 30-fold greater selectivity against PLK2 and no activity to PLK3. |
1225497-78-8 |
DC24085 |
Rigosertib sodium
Featured
Rigosertib sodium (ON 01910.Na) is a potent, non-ATP-competitive PLK1 inhibitor (IC50=9-10 nM), selectively induces mitotic G2/M arrest and apoptosis in cancer cells. |
592542-60-4 |
DC7266 |
Rilpivirine(R 278474, TMC 278)
Featured
Rilpivirine(R 278474, TMC 278) is a type of anti-HIV medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
500287-72-9 |
DC8985 |
Riluzole
Featured
Riluzole is a glutamate antagonist used as an anticonvulsant and to prolong the survival of patients with amyotrophic lateral sclerosis. |
1744-22-5 |
DC12800 |
BMS-927711(Rimegepant)
Featured
Rimegepant (BMS-927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM. |
1289023-67-1 |
DC9383 |
Rimonabant (Hydrochloride)
Featured
Rimonabant Hcl(SR141716A) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM. |
158681-13-1 |
DC8876 |
Rimonabant(SR141716)
Featured
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM. |
168273-06-1 |
DC7267 |
Riociguat (BAY 63-2521)
Featured
Riociguat (BAY 63-2521) is a stimulator of soluble guanylate cyclase (sGC). |
625115-55-1 |
DC10389 |
RIPA-56
Featured
RIPA-56 is a highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1) with an IC50 of 13 nM. |
1956370-21-0 |
DC21563 |
Risdiplam
Featured
Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA). |
1825352-65-5 |
DC1064 |
RITA (NSC652287)
Featured
RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells. |
213261-59-7 |
DC9475 |
Ritonavir
Featured
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS,showed potent activity against COVID-19(SARS-COV-2) . |
155213-67-5 |
DC5108 |
BAY 59-7939 (Rivaroxaban)
Featured
Rivaroxaban (Xarelto; BAY 59-7939) is a novel, oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. |
366789-02-8 |
DC12372 |
RK-24466
Featured
RK-24466 (KIN 001-51) is a potent and selective Lck inhibitor; inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively. |
213743-31-8 |
DC12436 |
RK-287107
Featured
RK-287107 (RK287107) is a novel potent, tankyrase-specific inhibitor with IC50 of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively, shows no activity against PARP-1. |
2171386-10-8 |
DC9761 |
RK-33
Featured
RK-33 is a novel DDX3 inhibitor for lung cancer therapy. |
1070773-09-9 |
DC8831 |
RKI-1313
Featured
RKI-1313 is the negative control for RKI-1447 which is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer |
1342276-76-9 |
DC7269 |
RKI-1447
Featured
RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2. |
1342278-01-6 |
DC12051 |
RMC-4550
Featured
RMC-4550 (RMC4550) is a potent, selective, allosteric inhibitor of SHP2 with IC50 of 0.58 nM (full-length SHP2 enzyme), suppresses pERK signaling in Calu-1 cells with IC50 of 7 nM. |
2172651-73-7 |