Cat. No. | Product name | CAS No. |
DC82003 |
A12-Iso5-2DC18
Featured
A12-Iso5-2DC18 is a novel amine containing lipid can be used for mRNA delivery, activate the stimulator of interferon genes (STING) pathway, and exhibit anti-tumor immunity. |
2412492-06-7 |
DC60311 |
Adaptaquin
Featured
Adaptaquin is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PHD2), with an IC50 of 2 μM. Adaptaquin can inhibit lipid peroxidation and maintain mitochondrial function[1][2]. |
385786-48-1 |
DC60317 |
(E/Z)-ZINC09659342
Featured
(E/Z)-ZINC09659342 is an inhibitor of Lbc-RhoA interaction[1]. |
591726-26-0 |
DC60319 |
sigma-1 Receptor antagonist 1
Featured
Sigma‑1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor (Ki = 1.06 nM). Sigma‑1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic pain[1]. |
1639220-19-1 |
DC60320 |
sigma-1 Receptor antagonist 2
Featured
Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively[1]. |
1639220-15-7 |
DC60321 |
WAY-352753 (GSK3-IN-1)
Featured
GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM. GSK3-IN-1 can be used in the research of diabetes[1]. |
478482-74-5 |
DC60322 | CYM 50358 hydrochloride Featured | 1781750-72-8 |
DC82030 |
MYF-03-176
Featured
MYF-03-176 is an orally active and potent anticancer agent. MYF-03-176 shows strong antitumor efficacy in MPM mouse xenograft model via oral administration[1]. |
2857937-59-6 |
DC60323 |
Dopamine D2 receptor agonist-2
Featured
Dopamine D2 receptor agonist-2 (compound 36) is a potent dopamine D2 receptor biased agonism ligand with an Ki value of 11.2 nM. Dopamine D2 receptor agonist-2 can be used to research antipsychosis[1]. |
1610591-93-9 |
DC60324 |
WAY-622024
Featured
WAY-622024(Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders. |
291528-35-3 |
DC60325 |
Olvanil
Featured
Olvanil (NE-19550)is an agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with an EC50 of 0.7 nM.Analgesic[1]. |
58493-49-5 |
DC60326 |
PQM130
Featured
PQM130, a Feruloyl-Donepezil Hybrid compound with brain penatration, is a multitarget drug candidate against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity. PQM130 acts as a neuroprotective compound for anti-AD drug development[1]. |
2089415-51-8 |
DC60327 | BPTF-IN-BZ1 Featured | 2766623-38-3 |
DC60328 |
PKR-IN-C51
Featured
PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1]. |
1314594-23-4 |
DC60329 |
c-Fms-IN-13
Featured
c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor with an IC50 value of 17 nM. c-Fms-IN-13 can be used as an anti-inflammatory agent[1]. |
885704-58-5 |
DC60330 |
RLX-33
Featured
RLX-33 is a potent, selective and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist, also blocks relaxin-3-induced ERK1/2 phosphorylation, with IC50 values of 2.36 μM for RXFP3, 7.82 and 13.86 μM for ERK1 and ERK2 phosphorylation, respectively. RLX-33 can block the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats. RLX-33 can be used for the research of metabolic syndrome[1]. |
2784577-71-3 |
DC60331 |
ISR-IN-1
Featured
ISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response. |
1628478-15-8 |
DC60332 |
ISRIB-A15
Featured
ISR-IN-2 (Compound 47) is an inhibitor of the integrated stress response . |
1628478-12-5 |
DC82032 |
Methoxy-X04
Featured
Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. |
863918-78-9 |
DC60333 |
BRD7586
Featured
BRD-7586(BRD 7586) is a cell-permeable small molecule inhibitor of SpCas9 with EC50 of 6.2 µM and 5.7 µM in the eGFP-disruption and HiBiT-knock-in assays, respectively. BRD7586 specifically engages SpCas9 but not Cas12a in cells and enhances SpCas9 specificity at multiple loci. |
895460-70-5 |
DC82050 |
Coelenterazine H
Featured
Coelenterazine h is a derivative of Coelenterazine. Coelenterazine h is more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations. |
50909-86-9 |
DC60335 |
Centanamycin
Featured
Centanamycin alkylates the A-T-rich minor groove of the DNA and thereby blocks DNA replication. Centanamycin potently inhibits replication of human cytomegalovirus (HCMV), mouse CMV (MCMV), and herpes simplex virus-2 (HSV-2) in vitro. Centanamycin-attenuated whole virion MCMV elicits a robust serum neutralizing antibody response and protects the mice from live-virus challenge. |
413577-16-9 |