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Cat. No. Product Name Field of Application Chemical Structure
A410 Finotonlimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Finotonlimab (SCT-I10A) is a recombinant humanised IgG PD-1 antibody. Finotonlimab has the potential for solid tumors or lymphomas research.
A411 Geptanolimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Geptanolimab (CBT-501) is a humanized IgG4k monoclonal antibody against programmed death-1 (PD-1). Siplizumab inhibits the binding of PD-L1/L2 to PD-1 through a competitive action. Siplizumab can be used in research of cancer.
A412 Iparomlimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Iparomlimab is an anti-human PD-1/CD279/PDCD1 IgG4κ antibody. Iparomlimab also targets to human monoclonal PSB103 γ4-chain, disulfided with human monoclonal PSB103 κ-chain to form a dimer. Iparomlimab can be used for Oncology research.
A413 Pidilizumab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Pidilizumab (CT-011) is a humanized IgG1k anti-PD-1 monoclonal antibody. Pidilizumab acts as a DLL1 antagonist. Pidilizumab has the potential for hematologic malignancies research.
A414 Sasanlimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Sasanlimab (PF-06801591) is a humanized IgG4-κ antibody targeting PD-1. Mainly expressed by CHO (Chinese Hamster Ovary) cells.
DC67045 Solriamfetol Featured Solriamfetol (JZP-110) is a selective dopamine and norepinephrine reuptake inhibitor with robust wake-promoting effects. Solriamfetol binds to dopamine and norepinephrine transporters, so it can inhibit reuptake of dopamine and norepinephrine. Solriamfetol treatment significantly improves the ability to stay awake and subjective symptoms of excessive sleepiness in adults with narcolepsy.
A415 Spartalizumab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Spartalizumab (PDR001) is a humanized immunoglobulin 4 monoclonal antibody that binds PD-1 with subnanomolar activity and blocks interaction with PD-L1 and PD-L2. Spartalizumab can be used for the research of anaplastic thyroid carcinoma (ATC).
A416 Pimivalimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Pimivalimab (JTX-4014) is a PD-1 inhibitor. Pimivalimab can be used for the research of solid tumor.
A417 Toripalimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Toripalimab is the first domestic anti-tumor PD-1 antibody in China. Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma.
A418 Zimberelimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Zimberelimab (GLS-010) is a fully human IgG4 anti-PD-1 monoclonal antibody with an EC50 of 210 pM for human PD-1. Zimberelimab effectively blocks the binding of PD-L1 and PD-L2 to cell-surface PD-1 in CHO-S cells, with IC50 values of 580 pM and 670 pM, respectively. Zimberelimab shows antitumor activities, and can be used for various cancers research, including cervical cancer, non-small cell lung cancer and classical Hodgkin’s lymphoma.
A419 Prolgolimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Prolgolimab (BCD-100) is a human IgG1 anti-PD-1 monoclonal antibody containing the Fc-silencing 'LALA' mutation. Prolgolimab can be used for the research of advanced melanoma.
A420 Nofazinlimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Nofazinlimab (CS1003) is a humanised IgG4 anti-PD-1 monoclonal antibody. Nofazinlimab can be used for unresectable hepatocellular carcinoma (uHCC) research.
A421 Cetrelimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Cetrelimab (JNJ 63723283; JNJ 3283) is a human IgG4κ mAb targeting PD-1. Cetrelimab binds PD-1 (Kd=1.72 nM, HEK293) to block the interaction of PD-1 with PD-L1 and PD-L2 (IC50s=111.7 ng/mL and 138.6 ng/mL, respectively). Cetrelimab stimulates peripheral T cells, increases IFN-γ, IL-2, TNF-α level and inhibits tumor growth in vivo.
A422 Budigalimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Budigalimab (ABBV 181; PR 1648817) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab is Fc mutated thus to reduce Fc receptor interactions and limit effector function.
A423 Ezabenlimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Ezabenlimab (BI-754091) is an anti-PD-1 mAb with binding constant Kd value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo.
A424 Serplulimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Serplulimab (HLX 10) is humanized monoclonal anti-PD-1 antibody. Serplulimab can be used in research of small cell lung cancer.
A425 Penpulimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Penpulimab is an IgG1 backbone anti-PD-1 monoclonal antibody with antitumor activities.
A426 Balstilimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibod) Featured Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1.
A427 UCB patent anti-PD-1 Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured
A428 MOR-8457 Biosimilar(Anti-PDGFB Reference Antibody) Featured
A429 Thrombogenics patent anti-PDGF-C Biosimilar(Anti-PDGFC / VEGFE Reference Antibody) Featured
A430 Olaratumab Biosimilar(Anti-PDGFRA / CD140a Reference Antibody) Featured Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha (PDGFRα) human monoclonal IgG1 antibody with antitumor activity.
A431 Tovetumab Biosimilar(Anti-PDGFRA / CD140a Reference Antibody) Featured Tovetumab (MEDI-575) is an anti-PDGFRα monoclonal antibody that selectively blocks the PDGFRα signal transduction. Tovetumab can be used in the research of glioblastoma and non-small cell lung cancer (NSCLC).
A432 IMC-2C5 Biosimilar(Anti-PDGFRB / CD140b Reference Antibody) Featured
A433 Novo Nordisk patent anti-PGLYRP1 Biosimilar(Anti-PGLYRP1 / PGRP-S Reference Antibody) Featured
A434 Bavituximab Biosimilar(Anti-Phosphatidylserine Reference Antibody) Featured Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel (HY-B0015) and Carboplatin (HY-17393), have enhanced inhibition on non-small-cell lung cancer.
A435 ATH3G10 Biosimilar(Anti-Phosphorylcholine Reference Antibody) Featured
A436 Diaccurate patent anti-sPLA2-GIB Biosimilar(Anti-PLA2G1B Reference Antibody) Featured
A437 ATN-658 Biosimilar(Anti-PLAUR / uPAR / CD87 Reference Antibody) Featured
A438 Genentech anti-PMEL17 Biosimilar(Anti-PMEL Reference Antibody) Featured

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