PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1.

Precursor of MC1, which is a selective and potent inhibitor for COX-2, used as the radioligands for development as clinically useful PET radioligands.

MC1 is a selective and potent inhibitor for COX-2, and [11C]MC1 detected COX-2 in nonhuman primates after intracerebral injection of an inflammogen.

ZNL-0056 is an ATP-competitive inhibitor that targets both the Cys797 and Cys775 in the ATP binding site of EGFR, which is the first compound capable of targeting a nonconserved and partially buried Cys775.

Compound 181 is a selective and highly potent stabilizer of the 14-3-3σ/ERα complex. Compound 181 shows potency comparable to the natural product Fusicoccin-A.

ARUK2001607 is a potent, selective, and brain penetrant PI5P4Kγ inhibitor with Kd of 7.1 nM and pIC50 of 7.0, respectively.

JNJ-1802 is a potent, pan-serotype Dengue Virus NS4B (DENV) inhibitor (EC50's ranging from 0.057 to 11 nM against the four DENV serotypes.

Lipid 20b is an ionizable lipid containing a thiophene moiety (Thio-lipid) for mRNA delivery. Lipid 20b enables LNPs to transfect the liver and spleen. Lipid 20b is potent in mRNA delivery to the retina with no acute toxicity.

C14-O2 is an oxidized lipid for mRNA delivery. C14-O2-LNP is capable of potent and selective delivery of mRNA to blood monocytes. C14-O2 LNP is used to deliver a functional CD19-CAR mRNA and is shown to engineer functional CAR monocytes directly in situ.

Lipid 29d is an ionizable lipid containing a thiophene moiety (Thio-lipid) for mRNA delivery. Lipid 29d enables LNPs to transfect the lung and spleen.

1,2-didecanoyl-sn-glycero-3-phosphate is one kind of phosphatidic acid, which is a minor constituent of biological membranes is a simplest glycerophospholipid. It has glycerol backbone with phosphate present at C-3 position. The C-1 and C-2 positions are esterified with fatty acids.It is used as a component in the lipid bilayer to study how lipid geometry acts in coat protein I (COPI) vesicle fission, and maybe used to activate protein kinase C (PKC).