Cat. No. | Product name | CAS No. |
DC5037 |
BMS-536924
Featured
BMS-536924 is an ATP-competitive IGF-1R inhibitor with IC50 of 100 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2. |
468740-43-4 |
DC7897 |
BMS-582949 HCl
Featured
BMS-582949 is a dual action p38 Kinase Inhibitor. |
623152-17-0 |
DC3105 |
BMS-599626 (AC480)
Featured
BMS-599626 (AC480) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, respectively. |
714971-09-2 |
DC7730 |
Temsavir(BMS-626529)
Featured
BMS-626529 is a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T-cells. |
701213-36-7 |
DC9252 |
BMS-687453
Featured
BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays. |
1000998-59-3 |
DC9700 |
BMS-707035
Featured
BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity. |
729607-74-3 |
DC3114 |
Avagacestat (BMS-708163)
Featured
BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectively. |
1146699-66-2 |
DC3126 |
BMS754807
Featured
BMS-754807 is a potent and reversible inhibitor of IGF-1R/IR family kinases, inhibits IGF-1R, IR, Met, TrkA and TrkB with IC50 of 1.8 nM, 1.7 nM, 5.6 nM, 7.4 nM and 4.1 nM, respectively. |
1001350-96-4 |
DC9861 |
BMS-779788(XL-652)
Featured
BMS-779788(XL652) is a novel small-molecule modulator of the Liver X Receptor (LXR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic disorders. |
918348-67-1 |
DC10494 |
BMS813160
Featured
BMS-813160 is a dual CCR2/CCR5 chemokine antagonist. |
1286279-29-5 |
DC12670 |
BMS-817378 free base
Featured
BMS-817378 is a prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833. |
1174161-69-3 |
DC20815 |
BMS-823778
Featured
BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2. |
1140898-87-8 |
DC7154 |
BMS-833923 (XL-139)
Featured
BMS 833923 is an orally bioavailable inhibitor of Smo. It blocks binding of BODIPY cyclopamine (IC50 = 21 nM) and inhibits Gli activation in cell lines that express wild-type Smo or activated mutant forms of Smo (IC50s = 6-35 nM). BMS 833923 robustly inhi |
1059734-66-5 |
DC7090 |
BMS-863233 (XL-413)
Featured
BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. |
1169562-71-3 |
DC4175 |
BMS-911543
Featured
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, approximately 350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. |
1271022-90-2 |
DC23872 |
BMS-932481(BMS932481;BMS 932481)
Featured
BMS-932481 (BMS932481) is a potent, selective, orraly active γ-secretase modulator (GSM), shows selectivity for Aβ40 and Aβ42 reduction (IC50=6.6 nM) while sparing total Aβ levels both in vitro and in vivo. |
1263871-36-8 |
DC21092 |
BMS-955176
Featured
BMS-955176 (GSK-3532795) is a second-generation HIV-1 maturation inhibitor that exhibits potent activity (EC50=3.9±3.4 nM) against a library (n=87) of gag/pr recombinant viruses. |
1392312-45-6 |
DC20821 |
BMS-962212
Featured
BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM. |
1430114-34-3 |
DC10459 |
BMS-986020
Featured
BMS-986020 is an LPA1 antagonist. |
1257213-50-5 |
DC11923 |
BMS-986120
Featured
BMS-986120 (BMS986120) is a potent, selective, orally bioavailable, and reversible PAR4 antagonist with Kd of 0.098 nM for human PAR4. |
1478712-37-6 |
DC26073 |
BMS-986122
Featured
BMS-986122 is a potent positive allosteric modulator of μ-opioid receptor, significantly increases the inhibition of forskolin-stimulated adenylyl cyclase activity produced by an EC10 (30 pM) concentration of endomorphin-I in CHO-μ cells.. |
313669-88-4 |
DC11819 |
BMS-986142
Featured
BMS-986142 is a potent, selective, and reversible BTK (Bruton’s tyrosine kinase) inhibitor (BTK IC₅₀ = 0.5nM; human WB IC₅₀ = 90 nM). |
1643368-58-4 |