DC2092 |
Genistein
Featured
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Genistein is a highly specific inhibitor of protein tyrosine kinase (PTK). |
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DC2093 |
Genistin
Featured
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Genistin is an isoflavone glycoside found in soy-based products. Can be used as a negative control for the PTK inhibitor Genistein |
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DCAPI1064 |
mixtures of three isomers (Gentamicins C1, C2, and C1(subA).
Featured
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Gentamycin sulfate (Gentacycol) |
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DC7417 |
Genz-123346
Featured
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Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM. |
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DC10161 |
Gepotidacin
Featured
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Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. |
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DC7132 |
GF 109203X
Featured
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GF109203X is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor. |
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DC21043 |
GGTI 2417
Featured
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GGTI 2417 is the methyl ester prodrug of GGTI-2418, a highly potent, competitive, and selective inhibitor of GGTase I. |
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DC21044 |
GGTI 2418
Featured
|
GGTI 2418 (PTX 100) is a highly potent, competitive, and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI) with IC50 of 9.5 nM, displays 5,600-fold selectivity over FTase. |
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DC21042 |
GGTI-2147
Featured
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GGTI-2147 is a non-thiol peptidomimetic that inhibits GGTase I and blocks geranyl-geranylation of Rap1A (IC50=0.5 uM). |
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DC11246 |
Ghrelin agonist HM01
Featured
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Ghrelin agonist HM01 is a novel potent, orally available ghrelin (GHS-R) agonist with Ki of 1.42 nM (human GHS-R1a), induces potent activation of intracellular calcium signaling with EC50 of 1.25 nM. |
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DC10883 |
GI254023X
Featured
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GI254023X is a potent MMP9 and ADAM10 inhibitor with IC50s of 2.5 and 5.3 nM, respectively. |
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DC10490 |
GIBH-130
Featured
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GIBH-130 is a novel inhibitor of neuroinflammation effective in Alzheimer’s disease models. |
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DC7432 |
Givinostat (ITF2357)
Featured
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Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM. Phase 1/2. |
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DC10081 |
GJ103
Featured
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GJ103 is an active analog of the read-through compound GJ072. |
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DC10080 |
GJ103 (sodium salt)
Featured
|
GJ103 sodium salt is an active analog of the read-through compound GJ072. |
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DC9855 |
GK921
Featured
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GK921 is a transglutaminase 2 (TGase 2) inhibitor with average GI50 of 0.9 uM in cancer cell lines. |
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DC8118 |
GKT137831(Setanaxib)
Featured
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GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 140±40 nM and 110±30 nM; a potent inhibitor of fibrosis and hepatocyte apoptosis. |
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DC21049 |
Glabrescione B
Featured
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Glabrescione B (GlaB) is a small molecule binding to Gli1 zinc finger and impairing Gli1 activity by interfering with Gli1/DNA interaction, inhibits Hh signaling by impairing Gli1 function; inhibits the growth of Hedgehog-dependent tumor cells in vitro and in vivo, inhibits Gli1-dependent growth of cerebellum-derived normal progenitors; inhibits the growth of Gli-dependent medulloblastoma and tumor-derived stem-like cells; inhibits the growth of Gli-dependent basal cell carcinoma in vitro and in vivo. |
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DC10130 |
Glabridin
Featured
|
Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract |
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DC10818 |
ABT-493(Glecaprevir)
Featured
|
Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. |
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DC11296 |
GLP-26
Featured
|
GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM. |
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DC8375 |
GLPG0634 analogue
Featured
|
GLPG0634 (analog) is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents. |
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DC11803 |
GLPG-1690(Ziritaxestat)
Featured
|
GLPG-1690 is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM. |
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DC10753 |
GLPG-1837(ABBV-974)
Featured
|
GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator. |
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DC26048 |
GLS1 Inhibitor
Featured
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GLS1 inhibitor is an inhibitor of glutaminase 1 |
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DC21052 |
GLS 4(Morphothiadin)
Featured
|
GLS4 (Morphothiadin) is a potent inhibitor of HBV capsid assembly, inhibits HBV replication (EC50=62.24 nM) and reduces HBV-DNA levels in HepG.2.2.15 cells (IC50=14 nM), shows efficacy against ADV-resistant HBV mutations. |
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DC10003 |
PF-06291874(glucagon receptor antagonists-4)
Featured
|
glucagon receptor antagonists-4 is a highly potent glucagon receptor antagonist. |
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DC11543 |
Glumetinib
Featured
|
Glumetinib (SCC 244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM. |
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DC9529 |
Glutaminase C-IN-1
Featured
|
Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts. |
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DC11009 |
GLX351322
Featured
|
GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M. |
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