| DC9957 |
HMN-176
Featured
|
HMN-176 is a stilbene derivative which inhibits mitosis without significant effect on tubulin polymerization. |
|
| DC8768 |
HMN-214
Featured
|
HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM. |
|
| DC6314 |
Icatibant acetate
Featured
|
HOE-140 (Icatibant) is a potent and selective bradykinin B2 receptor antagonist (pA2 = 9.04). Also inhibits aminopeptidase N (Ki = 9.1 μM). |
|
| DC22129 |
HOIPIN-1(JTP-0819958;HOIP inhibitor-1)
Featured
|
HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the N |
|
| DC22108 |
HOIPIN-8
Featured
|
HOIPIN-8 (HOIP inhibitor-8) is a potent chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=11 nM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pa |
|
| DC9650 |
Homoharringtonine
Featured
|
Homoharringtonine(HHT) is a cytotoxic alkaloid from the evergreen tree. |
|
| DC5908 |
Honokiol
Featured
|
Honokiol(NSC-293100), a hydroxylated biphenyl compound isolated from the Chinese herb Magnolia officinalis, has been reported to have anticancer activities in a variety of cancer cell lines. |
|
| DC7424 |
HPGDS-inhibitor-1
Featured
|
HPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM. |
|
| DC23978 |
hPGDS-IN-1
Featured
|
hPGDS-IN-1 is a potent, selective hPGDS inhibitor with IC50 of 12 nM in FP or EIA assays.. |
|
| DC23894 |
HPI-1
Featured
|
HPI-1 is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Shh (IC50=1.5 uM) without significantly affecting Wnt signaling (IC50>30 uM). |
|
| DC7962 |
HPOB
Featured
|
HPOB is a novel selective inhibitor of HDAC6 catalytic activity in vivo and in vitro. |
|
| DC10837 |
HS-10
Featured
|
HS-10 is a novel Hsp90 inhibitor increases the Tm of Hsp90 by 10.5°C. |
|
| DC12494 |
HS-10296
Featured
|
HS-10296 is an orally available inhibitor of the epidermal growth factor receptor (EGFR) mutant form T790M, with potential antineoplastic activity. |
|
| DC12045 |
HS-1371
Featured
|
HS-1371 is a novel kinase inhibitor of RIP3-mediated necroptosis. |
|
| DC11128 |
HS148
Featured
|
HS148 (DAPK3 inhibitor HS148) is a selective DAPK3 inhibitor with Ki of 119 nM, >10-fold selectivity over Pim kinases.. |
|
| DC7426 |
HS-173
Featured
|
HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM. |
|
| DC12632 |
HS220
Featured
|
HS220 (HS-220) is a Plasmodium-selective takinib analog that targets atypical P. falciparum protein kinase 9 (PfPK9, Kd=4.1 uM) but does not inhibit HsTAK1, decreases K63-linked ubiquitination in P. falciparum; inhibits P. berghei parasite load in HuH7 ce |
|
| DC10831 |
HS-27
Featured
|
Hs-27 is a Novel Hsp90 Inhibitor, Exhibits Diagnostic and Therapeutic Potential in Triple Negative Breast Cancer. |
|
| DC21124 |
HS-38
Featured
|
HS-38 is a potent and selective DAPK1 and DAPK3 (ZIPK) inhibitor with IC50 of 200 nM for DAPK1 and Kd of 280 nM for ZIPK, also inhibits Pim3 (IC50=200 nM), and displays no activity against Src or Abl, little activity against EGFR; |
|
| DC11127 |
HS94
Featured
|
HS94 (DAPK3 inhibitor HS94) is a selective DAPK3 inhibitor with Ki of 126 nM, >20-fold selectivity over Pim kinases.. |
|
| DC10614 |
HSF1A
Featured
|
HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1). |
|
| DC10344 |
HSP70-IN-1
Featured
|
HSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM. |
|
| DC4178 |
NVP-HSP990 (HSP990)
Featured
|
HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. |
|
| DC12493 |
HT-2157(SNAP37889)
Featured
|
HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3). |
|
| DC7705 |
HTH-01-015
Featured
|
HTH-01-015 is a selective inhibitor of NUAK1 kinase with an IC50 value of 100 nM. |
|
| DC9960 |
HTHQ
Featured
|
HTHQ, which is a hydroquinone monoalkyl ether, is a potent anti-oxidative agent, even at low dose levels. |
|
| DC9697 |
HUHS015
Featured
|
HUHS015 is a prostate cancer antigen (PCA)-1/AlkB homologue 3 (ALKBH3) inhibitor. |
|
| DC12262 |
H-Val-Pro-Pro-OH TFA
Featured
|
H-Val-Pro-Pro-OH (TFA) is a trifluoroacetate (TFA) salt form of the tripeptide H-Val-Pro-Pro-OH, which is derived from milk proteins. This peptide is known for its ability to inhibit Angiotensin I Converting Enzyme (ACE), a key enzyme in the renin-angiotensin system (RAS) that regulates blood pressure. The TFA salt form is commonly used in research and pharmaceutical applications to improve the solubility and stability of the peptide. |
|
| DC20081 |
H-Val-Pro-Pro-OH
Featured
|
H-Val-Pro-Pro-OH is a tripeptide derived from milk proteins, specifically a proline-rich peptide, and is known for its inhibitory activity against Angiotensin I Converting Enzyme (ACE). ACE is a key enzyme in the renin-angiotensin system (RAS), which regulates blood pressure by converting angiotensin I to angiotensin II, a potent vasoconstrictor. Inhibition of ACE leads to reduced angiotensin II levels, resulting in vasodilation and lowered blood pressure. |
|
| DC10580 |
hVEGF-IN-1
Featured
|
hVEGF-IN-1 represses human VEGF-A translation and shows antitumor activity. |
|
