| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21993 | ALDH1A inhibitor 673A | ALDH1A inhibitor 673A (ALDH1Ai 673A) is a potent, selective, pan-ALDH1A inhibitor with IC50 of 246, 230 and 348 nM for ALDH1A1, ALDH1A2 and ALDH1A3, respectively. |
|
| DC11024 | ALDH3A1 inhibitor EN40 | ALDH3A1 inhibitor EN40 is a potent and selective, covalent, in vivo-active inhibitor of ALDH3A1 with IC50 of 2 uM, demonstrates no activity against ALDH1A3 and ALDH6A1 at 30 uM. |
|
| DC20653 | ALE-0540 Featured | ALE-0540 is a nerve growth factor (NGF) antagonist that inhibits the binding of NGF to TrkA or both p75 and TrkA with IC50 of 5.88 and 3.72 uM, respectively. |
|
| DCAPI1034 | Alendronate (Fosamax) | Alendronate (Fosamax) |
|
| DC22492 | Alexamorelin Featured | Alexamorelin is a synthetic growth hormone (GH) secretagogue. |
|
| DC12389 | Alflutinib Featured | Alflutinib (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.The Alflutinib free base form is not stable, so we make it the mesylate s |
|
| DC12072 | Alflutinib (AST2818 mesylate) Featured | Alflutinib (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.. |
|
| DC9334 | Alfuzosin | Alfuzosin is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH). |
|
| DC22211 | ALG1001 (Risuteganib) Featured | ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis; ALG1001 inhibits an integrin-mediated pathway of the vitreoretinal interface, connecting the posterior aspect of the vitreous with the internal limiting membrane of the retina. In blocking this pathway, ALG-1001 helps to achieve vitreous breakdown and separation from the retina. |
|
| DC20056 | Alicapistat (ABT-957) | Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential use in the treatment of Alzheimer's disease (AD). |
|
| DCAPI1495 | Aliskiren Hemifumarate Featured | Aliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM. |
|
| DC23405 | Alizapride | Alizapride (MS 5080) is a dopamine D2 antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting.. |
|
| DC23489 | Alizapride hydrochloride | Alizapride (MS 5080) is a dopamine D2 antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting.. |
|
| DC23092 | Alizarin | Alizarin has a selective and effective inhibitory activity towards cancerous cells, it acts through the inhibition of ERK phosphorylation and cell cycle arrest in the S-phase. |
|
| DC9338 | ALK inhibitor 1 Featured | ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase. |
|
| DC9339 | ALK inhibitor 2 Featured | ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase. |
|
| DC10582 | Diroximel Fumarete(ALKS-8700) Featured | ALKS-8700 also known as diroximel fumarate, is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body. |
|
| DC11495 | Allitinib Featured | Allitinib (AST-1306, ALS1306)) is a novel potent, selective irreversible EGFR and HER2 inhibitor with IC50 of 0.5 and 3 nM in cell-free assays. |
|
| DC8106 | ALLM (Calpain Inhibitor) | ALLM (Calpain Inhibitor) is cell-permeable, peptide aldehyde inhibitor of calpains and cathepsins. |
|
| DC8570 | ALLO-1 Featured | ALLO-1 is a SMO antagonist that inhibits both wild-type (IC50 = 50 nM) and mutant SMO, including the D473H SMO mutant (IC50s = 300-1000 nM). |
|
| DC21668 | ALLO-2 Featured | ALLO-2 is a potent small molecule Smoothened (Smo) antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM. |
|
| DC12226 | Alloepipregnanolone | Alloepipregnanolone, a pregnane with anesthetic, hypnotic, and sedative properties, interferes with the development of rapid tolerance to the anxiolytic effect of ethanol. |
|
| DC10311 | Allopregnanolone Featured | Allopregnanolone is a progesterone metabolite. Allopregnanolone is an allosteric modulator of the GABA receptor. |
|
| DC8945 | Allopurinol | Allopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. |
|
| DC10303 | Allopurinol riboside | Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites. |
|
| DCAPI1097 | Allopurinol Sodium (Aloprim) Featured | Allopurinol sodium is a potent xanthine oxidase inhibitor (IC50 values of 0.2 to 50 μM). Allopurinol sodium can be used for the research of hyperuricemia and gout. Antileishmanial effect[1][2]. |
|
| DC20171 | Alloxazine;Isoalloxazine | Alloxazine is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor. |
|
| DC12060 | all-trans-4-Oxoretinoic acid | all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs). |
|
| DC7692 | Almorexant HCl (Act-078573) Featured | Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively. |
|
| DCAPI1478 | Almotriptan | Almotriptan |
|
