DC8284 |
Almotriptan Malate(PNU180638)
Featured
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Almotriptan Malate is a 5-HT1B/1D-receptor agonist used to treat migraine. |
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DC11887 |
Alobresib (GS-5829)
Featured
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Alobresib is a novel BET bromodomain inhibitor with antineoplastic activity.. |
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DC11931 |
Alofanib
Featured
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Alofanib ((RPT-835) is a potent, selective, allosteric FGFR2 inhibitor that significantly inhibits bFGF-induced proliferation of HUVEC cells with IC50 of 11 nM |
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DCAPI1579 |
Alogliptin |
Alogliptin |
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DC5076 |
Alogliptin Benzoate
Featured
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Alogliptin is an orally administered, anti-diabetic drug in the DPP-4 inhibitor class. A randomized clinical trial reporting in 2011 aimed to determine the efficacy and safety of alogliptin versus placebo and voglibose among newly diagnosed Type 2 diabete |
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DC10234 |
Alosetron Hydrochloride |
Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. |
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DC10735 |
Alovudine
Featured
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Alovudine is a DNA polymerase subunit gamma-1 (POLG) inhibitor, shows promise for treating AML. |
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DC9920 |
alpha-Hederin
Featured
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alpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation. |
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DC23079 |
α-mangostin
Featured
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Alpha-Mangostin has neuroprotective, anti-cancer, antifungal, neuroprotective, renoprotective, antioxidant and anti-inflammatory activities. |
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DC20940 |
Alprazolam |
Alprazolam (D-65MT, U 31889) is a triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. |
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DC26001 |
Alprenolol
Featured
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Alprenolol is a non-selective beta blocker as well as 5-HT1A receptor antagonist. |
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DCAPI1328 |
Alprostadil(Caverject)
Featured
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Alprostadil(Caverject) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases. |
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DC12656 |
Alrestatin
Featured
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Alrestatin is an AKR (aldose reductase) inhibitor, which attaches molecules to the active site of the NADP+/enzyme complex in a stacked formation. |
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DC8366 |
ALS22335
Featured
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ALS-22335 is an anti-virus compound. |
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DC23098 |
ALS-8112 |
ALS-8112 is a potent, selective RSV polymerase inhibitor, the 5'-triphosphate of ALS-8112 (ALS-8112-TP) inhibits RSV polymerase(IC50=20 nM) without appreciable inhibition of human DNA and RNA polymerases. |
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DC23144 |
ALS-8176 |
ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM. |
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DC9838 |
Alsterpaullone
Featured
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Alsterpaullone is a potent ATP-competitive and cell cycle cyclin-dependent kinase inhibitor, that is reported to be the most active Paullone. |
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DC8072 |
Altiratinib(DCC-2701)
Featured
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Altiratinib is a MET/TIE2/VEGFR2/TRK (A,B,C) kinase inhibitor in Phase 1 clinical development for the treatment of invasive solid tumors including glioblastoma. |
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DCAPI1290 |
Altretamine (Hexalen) |
Altretamine (Hexalen) |
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DC7079 |
Alvelestat (AZD9668)
Featured
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Alvelestat (AZD9668) is a novel, oral inhibitor of neutrophil elastase (NE) with the pIC50 of 7.9 for Human NE. |
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DCAPI1250 |
Alverine Citrate |
Alverine citrate is a drug used for functional gastrointestinal disorders. |
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DC8606 |
Alvimopan monohydrate |
Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
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DC8605 |
Alvimopan dihydrate |
Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
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DC10209 |
ALW-II-41-27
Featured
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ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor, used for cancer treatment. |
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DC23849 |
ALW-II-49-7 |
ALW-II-49-7 (DDR2-IN-1) is a potent, selective DDR2 inhibitor with IC50 of 18.6 nM, also shows ability to inhibit DDR1 and Ephrin-family kinases (IC50=40 nM for EphB2). |
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DC11840 |
ALX-1393 |
ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM. |
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DC23604 |
ALX-5407 hydrochloride
Featured
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ALX-5407 is a potent, selective, orally active inhibitor of GlyT1 glycine transporter with IC50 of 3 nM. |
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DC11301 |
ALZ-801
Featured
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ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease. |
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DC22431 |
AM432 sodium |
AM 432 is potent, selective, orally active prostaglandin D2 receptor (DP2/CRTH2) antagonist with binding IC50 of 6 nM for hDP2. |
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DC11182 |
AM-0216 |
AM-0216 (Amgen16) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 2 nM, selectively decrease viability of MMCLs in which NFkB activity is NIK-dependent. |
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