| DCAPI1343 |
Amorolfine HCl
Featured
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Amorolfine hydrochloride is a antifungal reagent. |
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| DC10698 |
Amoscanate
Featured
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Amoscanate(nithiocyamine) is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans,and is also highly active against hookworm |
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| DCAPI1158 |
Amoxicillin sodium (Amox) |
Amoxicillin sodium (Amox) |
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| DC5075 |
BDP-12(Ampalex)
Featured
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Ampalex (Ampakine CX516) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). |
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| DCAPI1309 |
Ampicillin sodium |
Ampicillin is a beta-lactam antibiotic that is part of the aminopenicillin family. |
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| DC9406 |
Ampiroxicam |
Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
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| DC11130 |
AMPK activator 991 |
AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively.. |
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| DC11129 |
AMPK activator SC4
Featured
|
AMPK activator SC4 is a highly specific and potent activator of the α2β2-AMPK complexes, which are the predominant AMPK isoform complexes found in human skeletal muscle. SC4 demonstrates significant efficacy with EC50 values of 17.2 nM for the α2β2γ1 complex and 82.1 nM for the α2β2γ3 complex. These low EC50 values indicate that SC4 is effective at relatively low concentrations, making it a promising compound for targeting AMPK in skeletal muscle. This specificity and potency suggest potential therapeutic applications in conditions where AMPK activation is beneficial, such as metabolic disorders, muscle function, and energy homeostasis. |
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| DC23111 |
Ampkinone |
Ampkinone is a novel small molecule activator of AMPK, stimulates the phosphorylation of AMPK via indirect activation of AMPK in various cell lines (2.7-fold at 10 uM). |
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| DC11274 |
AMPPD
Featured
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AMPPD, 1,2-dioxo-cyclohexane derivatives, is a new biochemistry ultrasensitive alkaline phosphatase substrate. |
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| DC11076 |
Ampreloxetine |
Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively. |
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| DC7058 |
Amprenavir
Featured
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Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. |
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| DC23625 |
AMR-2 |
AMR-2 is a highly potent, orally active, triple reuptake inhibitor of SERT, NET, and DAT with IC50 of 3.0, 3.1, and 8.3 nM, respectively. |
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| DC7002 |
Amrubicin(SM-5887) |
Amrubicin(SM-5887) is a novel anthracycline derivative for treatment of bladder carcinoma. |
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| DC9634 |
Amsacrine |
Amsacrine (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. |
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| DC7510 |
TAC-101 |
amsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. This agent also causes a cytotoxic decline in cyclin A and thymidylate synthase expression. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).For the detailed information of TAC-101, the solubility of TAC-101 in water, the solubility of TAC-101 in DMSO, the solubility of TAC-101 in PBS buffer, the animal experiment (test) of TAC-101, the cell expriment (test) of TAC-101, the in vivo, in vitro and clinical trial test of TAC-101, the EC50, IC50,and Affinity of TAC-101, Please contact DC Chemicals.. |
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| DC7324 |
Amuvatinib (MP-470)
Featured
|
Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. |
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| DC20088 |
Amuvatinib hydrochloride (MP470 hydrochloride; HPK 56 hydrochloride) |
Amuvatinib hydrochloride (MP470 hydrochloride) is a multi-targeted receptor tyrosine kinases inhibitor, which inhibits c-Kit (D816V), c-Kit (D816H), c-Kit (V560G), c-Kit (V654A), PDGFRα (D842V), and PDGFRα (V561D) with IC50s of 950 nM, 10 nM, 34 nM, 127 n |
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| DC21995 |
AMXT-1501 |
AMXT-1501 (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination of with DFMO. |
|
| DC21996 |
AMXT-1501 tetrahydrochloride |
AMXT-1501 tetrahydrochloride (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination with DFMO. |
|
| DC23109 |
AMZ30 |
AMZ30 is a potent, selective, covalent inhibitor of the serine hydrolase protein phosphatase methylesterase-1 (PME-1) with IC50 of 0.6 uM, >100-fold selectivity over other SHs. |
|
| DC25088 |
Rivastigmine
Featured
|
An acetylcholinesterase (AChE) inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. |
|
| DC11651 |
HLY-78
Featured
|
HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction[1]. |
|
| DC22762 |
Norendoxifen |
An active metabolite of the selective estrogen receptor modulator (SERM) tamoxifen. |
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| DC23227 |
N6-Cyclohexyladenosine
Featured
|
An adenosine A1 receptor agonist (EC50= 8.2 nM).. |
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| DC24153 |
Cysteamine hydrochloride |
An agent for the treatment of nephropathic cystinosis and an antioxidant. |
|
| DC23931 |
Hydrastine |
An alkaloid of Hydrastis canadensis used in many dietary supplements intended to enhance the immune system. |
|
| DC11657 |
PPT(Propyl pyrazole triol )
Featured
|
Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). |
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| DC21630 |
SCF-I2 |
An allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assyas. |
|
| DC22888 |
β2AR-IN-15 |
An allosteric, small-molecule negative modulator for β2AR with Kd of 1.7 uM. |
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