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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC10839 CIL56(CA3) Featured CIL56 is a small molecule that induces cellular ferroptosis through production of iron-dependent reactive oxygen species (ROS).
DC11374 Cilastatin Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase.
DCAPI1569 Cilostazol Cilastazol is a 2-oxo-quinoline with vasodilator, antimitogenic, antithrombotic, and cardiotonic properties. This compound has been shown to cause inhibition of adenosine uptake, eventually resulting in changes to cAMP levels. Studies have shown Cilostazo
DC9325 Cilazapril (monohydrate) Featured Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
DC7561 Cilengitide (TFA salt) Featured Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
DC9875 Ciliobrevin A(HPI4) Featured Ciliobrevin A(HPI-4) is a Hedgehog pathway inhibitor and ciliogenesis inhibitor.
DC20341 Ciliobrevin D Featured Ciliobrevin D is a cell-permeable, reversible, specific inhibitor of cytoplasmic dynein, blocks dynein-dependent microtubule gliding and ATPase activity while sparing kinesin dependent cellular trafficking.
DC9160 Cilnidipine Featured Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
DC10868 Cilofexor Featured Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.
DC9582 Cilomilast Cilomilast(SB 207499; Ariflo) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity.
DC22028 Ciluprevir Ciluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively.
DC9002 Cimetidine Cimetidine is a histamine-2 (H2) receptor antagonist.
DC12134 Cimiside B Cimiside B, a glycoside alkaloid, isolated from the rhizome of Cimicifuga dahurica.
DC8801 Cinacalcet (AMG-073) Featured Cinacalcet(AMG-073) is an orally active, second-generation calcimimetic compound; AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism.
DC12369 Cinaciguat (hydrochloride) Featured Cinaciguat is an activator of sGC that binds to a regulatory site, resulting in activation in an NO-independent manner (Kd = 3.2 nM).
DC20093 Cinchonine ((8R,9S)-Cinchonine; LA40221) Featured Cinchonine is a natural compound present in Cinchona bark. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells.
DC9174 Cinepazide maleate Cinepazide Maleate is a vasodilator.
DC9896 Cinnarizine Featured Cinnarizine is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker.
DCH-062 Cinobufotalin Featured Cinobufotalin is a steroid glycoside originally isolated from the Asiatic toad (B. gargarizans) and has diverse biological activities.
DC22295 Cintirorgon sodium Featured Cintirorgon (LYC-55716) is novel oral RAR-related orphan receptor γ (RORγ) agonist.
DC22329 Cintirorgon Featured Cintirorgon (LYC-55716) is novel oral RAR-related orphan receptor γ (RORγ) agonist.
DC21572 Cipemastat Cipemastat (Ro 32-3555) is a potent, second-generation, orally active MMP inhibitor, preferentially inhibits collagenases (MMP-1, -8, and -13) and gelatinase B (MMP-9).
DC9603 Ciprofibrate Ciprofibrate is a peroxisome proliferator-activated receptor agonist.
DCAPI1372 Ciprofloxacin (Cipro) Featured Ciprofloxacin (Bay-09867) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
DC2062 Ciproxifan (FUB-359) Featured Ciproxifan is an antagonists of H3-type histamine receptors.
DC9466 Ciproxifan (maleate) Featured Ciproxifan maleate(FUB-359 maleate) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.
DC8156 CIQ Featured CIQ is a positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively).
DC8187 Ciraparantag(PER977) Featured Ciraparantag(PER977) is an intravenously administered anticoagulant Reversal Agent.
DC12100 Cirsimaritin Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.
DC20342 cis Ned-19 cis Ned-19 is the stereoisomer of trans Ned-19, a chemical probe for the Ca(2+)-releasing second messenger NAADP.

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