Cat. No. | Product name | CAS No. |
DC11905 |
Opiranserin
Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM). |
1441000-45-8 |
DC7262 |
Optovin
Featured
Optovin is a reversible photoactive TRPA1 activator. |
348575-88-2 |
DC10394 |
Org-26576
Org 26576 is a AMPA receptor positive allosteric modulator. |
100044-96-0 |
DC9001 |
Oxcarbazepine
Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM. |
28721-07-5 |
DC10399 |
PAC-14028
PAC-14028 is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist. |
1005168-10-4 |
DC10292 |
Pagoclone
Pagoclone is an active (+)-enantiomer of the racemate RP 59037. Pagoclone is a partial GABA(A) receptor agonist used for the treatment of panic and anxiety disorders. |
133737-32-3 |
DC9876 |
Pantoprazole
Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
102625-70-7 |
DC9135 |
Pantoprazole Sodium
Pantoprazole sodium salt(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
138786-67-1 |
DC9098 |
Paroxetine HCl
Featured
Paroxetine hydrochloride hemihydrate is a antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). |
110429-35-1 |
DC7989 |
PEPA
Featured
PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. |
141286-78-4 |
DC7226 |
Perampanel(E2007)
Featured
Perampanel(E2007; ER 155055-90) is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical trials. |
380917-97-5 |
DC10356 |
PF 03716556
PF 03716556 is a potent, and selective acid pump (H+,K+ ATPase) antagonist, with pIC50 value of 6.009. |
928774-43-0 |
DC10529 |
PF 05089771
Featured
PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM. |
1235403-62-9 |
DC10038 |
PF-01247324
Featured
PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain. |
875051-72-2 |
DC3108 |
PF-04971729 (Ertugliflozin)
Featured
PF-04971729 is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials for the treatment of diabetes mellitus. |
1210344-57-2 |
DC12334 |
PF-05241328
PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM. |
1387633-03-5 |
DC11966 |
PF-06678419
PF-06678419 (PF06678419) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.44 uM. |
2055468-48-7 |
DC10834 |
PF-06869206
Featured
PF-06869206 is an Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1). |
2227425-05-8 |
DC11188 |
PF-4778574
PF-4778574 (PF4778574) is a brain penetrant, positive allosteric modulator (potentiator) of AMPA receptor with Ki of 85 nM, increases S-AMPA-evoked responses in rat primary cortical neurons with EC50 of 45-919 nM. |
1219633-99-4 |
DC9024 |
Phenytoin sodium
Phenytoin sodium is an inactive voltage-gated sodium channel stabilizer. |
630-93-3 |
DC10763 |
Philanthotoxin 74 (hydrochloride)
Featured
Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. |
1227301-51-0 |
DCAPI1588 |
Pilsicainide hydrochloride
Pilsicainide hydrochloride is a selective Na+ channel blocker (IC30 values are 9 and 60 μM for inward Na+ and Ca2+ currents respectively). Shows antiarrhythmic effects in vivo. Orally active. |
88069-49-2 |