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Cat. No. Product name CAS No.
DC11905 Opiranserin

Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM).

1441000-45-8
DC7262 Optovin Featured

Optovin is a reversible photoactive TRPA1 activator.

348575-88-2
DC10394 Org-26576

Org 26576 is a AMPA receptor positive allosteric modulator.

100044-96-0
DC9001 Oxcarbazepine

Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.

28721-07-5
DC10399 PAC-14028

PAC-14028 is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist.

1005168-10-4
DC10292 Pagoclone

Pagoclone is an active (+)-enantiomer of the racemate RP 59037. Pagoclone is a partial GABA(A) receptor agonist used for the treatment of panic and anxiety disorders.

133737-32-3
DC9876 Pantoprazole

Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

102625-70-7
DC9135 Pantoprazole Sodium

Pantoprazole sodium salt(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

138786-67-1
DC9098 Paroxetine HCl Featured

Paroxetine hydrochloride hemihydrate is a antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).

110429-35-1
DC7989 PEPA Featured

PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.

141286-78-4
DC7226 Perampanel(E2007) Featured

Perampanel(E2007; ER 155055-90) is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical trials.

380917-97-5
DC10356 PF 03716556

PF 03716556 is a potent, and selective acid pump (H+,K+ ATPase) antagonist, with pIC50 value of 6.009.

928774-43-0
DC10529 PF 05089771 Featured

PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM.

1235403-62-9
DC10038 PF-01247324 Featured

PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain.

875051-72-2
DC3108 PF-04971729 (Ertugliflozin) Featured

PF-04971729 is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials for the treatment of diabetes mellitus.

1210344-57-2
DC12334 PF-05241328

PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM.

1387633-03-5
DC11966 PF-06678419

PF-06678419 (PF06678419) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.44 uM.

2055468-48-7
DC10834 PF-06869206 Featured

PF-06869206 is an Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1).

2227425-05-8
DC11188 PF-4778574

PF-4778574 (PF4778574) is a brain penetrant, positive allosteric modulator (potentiator) of AMPA receptor with Ki of 85 nM, increases S-AMPA-evoked responses in rat primary cortical neurons with EC50 of 45-919 nM.

1219633-99-4
DC9024 Phenytoin sodium

Phenytoin sodium is an inactive voltage-gated sodium channel stabilizer.

630-93-3
DC10763 Philanthotoxin 74 (hydrochloride) Featured

Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.

1227301-51-0
DCAPI1588 Pilsicainide hydrochloride

Pilsicainide hydrochloride is a selective Na+ channel blocker (IC30 values are 9 and 60 μM for inward Na+ and Ca2+ currents respectively). Shows antiarrhythmic effects in vivo. Orally active.

88069-49-2
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