| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10619 | UCPH-101 Featured | UCPH-101 is a selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor. |
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| DC11197 | UoS12258 Featured | UoS12258 (UoS-12258) is a selective, positive allosteric modulator of the AMPA receptor with pEC50 of 5.6. |
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| DC9813 | Valspodar(PSC833) Featured | Valspodar(PSC833) is a P-glycoprotein (P-gp) inhibitor widely used in preclinical and clinical studies for overcoming multidrug resistance (MDR). |
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| DC8916 | Vanoxerine dihydrochloride Featured | Vanoxerine 2 Hcl(GBR12909) is a potent and selective DRI (Dopamine reuptake inhibitor). |
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| DC8429 | Verdinexor (KPT-335) Featured | Verdinexor (KPT-335) is an orally bioavailable, selective XPO1/CRM1 inhibitor. |
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| DC10029 | Verinurad Featured | Verinurad is an urate transporter inhibitor with EC50 value of 0.05 μM.Verinurad is useful in the modulation of blood or serum uric acid levels, reducing serum uric acid levels in a human. |
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| DC9560 | Vigabatrin (Hydrochloride) | Vigabatrin Hcl(γ-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase. |
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| DC9541 | Vigabatrin Featured | Vigabatrin(γ-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase. IC50 value: Target: GABA transaminase Clinical studies have sh |
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| DC5016 | Vilazodone hydrochloride | Vilazodone (EMD 68843) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation. |
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| DC7100 | CFTRinh 172 Featured | Voltage-independent, selective CFTR chloride channel blocker (Ki = 300 nM) that alters channel gating. |
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| DC12169 | VU0463271 | VU0463271 is a potent KCC2 antagonist, with an IC50 of 61 nM. |
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| DC7531 | VX661 Featured | VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. |
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| DC1059 | Lumacaftor(vx-809，vx809) Featured | VX-809 is a CFTR modulator with EC50 of 0.1 μM. |
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| DC10493 | WZB117 Featured | WZB117 is an irreversible inhibitor of glucose transporter 1 (Glut1) that blocks glucose transport in diverse cancer cells (IC50 = ~0.6 µM), reducing extracellular lactate and intracellular ATP levels. |
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| DC9369 | YHO-13177 Featured | YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells. |
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| DC9962 | YM-58483 Featured | YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. |
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| DC7753 | Zatebradine hydrochloride | Zatebradine hydrochloride is a bradycardic agent that creates use-dependent inhibition of hyperpolarization-activated current (If) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres. |
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| DC9461 | Zatebradine | Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM. |
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| DC7754 | ZK-200775 | ZK 200775 is a competitive GluR (AMPA)/kainate antagonist. |
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| DC7642 | Α5ia (α5IA) | α5IA is a selective inverse agonist for Α5 subtype of GABAA receptor with a higher intrinsic activity at the A5 subtype than other drugs. |
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| DC8774 | KPT 251 Featured | KPT-251 is a selective inhibitor of nuclear export (SINE). |
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| DC11117 | KRM-II-81 |
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| DC11145 | WAY213613 Featured | WAY-213613 (WAY213613) is a potent, non-substrate inhibitor of EAAT2 (GLT-1) with IC50 of 85 nM, displays > 44-fold selectivity over EAAT1 and EAAT3; also exhibits no activity towards ionotropic and metabotropic glutamate receptors. |
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| DC9094 | Ropivacaine mesylate |
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| DC9066 | Quinidine |
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| DC11941 | VU590 dihydrochloride |
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| DC11945 | VU714 oxalate |
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| DC11144 | NBI-59159 Featured |
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| DC8902 | PNU282987 Featured |
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| DC28070 | A-887826 | A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo. |
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