| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9076 | Sertraline HCL | Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
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| DC11376 | SKA-121 Featured | SKA-121 is a positive-gating modulator of intermediate-conductance calcium-activated potassium channels (IKCa1/KCa3.1) with an EC50 value of 109 nM using whole-cell patch-clamp electrophysiology with calcium in the internal solution. |
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| DC7834 | SKF 89976A HCl Featured | SKF-89976A was used to study the role of adenosine receptors in uptake of GABA transport. |
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| DC9722 | SKF96365 Featured | SKF96365 is blocker of TRP cation channels. Inhibits capacitative Ca2+ entry. |
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| DC9622 | SN 2 | SN 2 is a novel and potent small molecule activator of TRPML3 with EC50 of 1.13 uM. |
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| DC7287 | Ralfinamide Featured | Sodium channel blocker. Suppresses tetrodotoxin (TTX)-resistant Na+ currents approximately twice as selectively as TTX-sensitive currents. Antinociceptive; displays analgesic effects in animal models of inflammatory and neuropathic pain. |
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| DC7505 | Sodium-Channel-inhibitor-1 | Sodium Channel inhibitor1, one of 3-Oxoisoindoline-1-carboxamides, is a novel and selective voltage-gated sodium channel for pain treatment. |
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| DC11529 | Solriamfetol hydrochloride Featured | Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
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| DC11242 | SRI-31142 | SRI-31142 (SRI31142) is a novel potent, putative allosteric dopamine transporter (DAT) inhibitor with Ki of 1.9 nM.. |
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| DC10651 | SSD114 hydrochloride Featured | SSD114 is a novel GABAB positive allosteric modulator. |
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| DC8359 | STF-31 Featured | STF-31 is an inhibitor of GLUT1 (IC50 = ~1 µM) that blocks glucose uptake. |
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| DC8308 | SYM2206 | SYM2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). |
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| DC7306 | TAK-438 Featured | TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. |
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| DC7863 | Talampanel (GYKI 53773) Featured | Talampanel is a novel anticonvulsant that acts as an allosteric inhibitor of the AMPA receptor. |
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| DC1102 | Tariquidar (XR9576) Featured | Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM. |
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| DC10331 | Tebanicline hydrochloride | Tebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM. |
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| DC10386 | Tenapanor Featured | Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively. |
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| DC11947 | ML418 Featured | The first potent, selective, CNS penetrating inward rectifier potassium channel Kir7.1 (KCNJ13) inhibitor with IC50 of 0.31 uM. |
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| DC11940 | VU590 | The first small-molecule inhibitor of renal outer medullary potassium channel (ROMK, Kir1.1) and Kir7.1 with IC50 of 294 nM for ROMK. |
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| DC8896 | Tiagabine hydrochloride Featured | Tiagabine(NO328) is a selective gamma-aminobutyric acid (GABA) reuptake inhibitor. |
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| DC7826 | Tofogliflozin hydrate | Tofogliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2). |
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| DC11357 | Tolazamide | Tolazamide is a first generation sulfonylurea that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2; IC50 = 4.2 µM in HEK293 cells transfected with the human receptor). |
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| DC9023 | Tolbutamide | Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic drug. |
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| DC11319 | TPMPA Featured | TPMPA is a GABAA-ρ1 (ρ1 GABAC) receptor antagonist that is 8-fold selective for GABAA-ρ1 over GABAA-ρ2 (ρ2 GABAC) receptors expressed in X. |
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| DC9598 | TRAM-34 Featured | TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). |
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| DC12170 | Transcrocetinate disodium (Disodium trans-crocetinate) | Transcrocetinate disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. |
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| DC8824 | Traxoprodil Featured | Traxoprodil is an NMDA ε 2 (NR2B) antagonist that has been studied as an alternative to serotonin selective reuptake inhibitors. |
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| DC7755 | TRCP6 inhibitor(SAR7334) Featured | TRPC6 inhibitor is a potent TRPC6(Transient receptor potential cation channel, subfamily C, member 6) inhibitor. |
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| DC11472 | TRPM8 antagonist 14 Featured | TRPM8 Antagonist is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes. |
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| DC9958 | U 93631 Featured | U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors. |
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