| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9967 | SQ22536 Featured | SQ 22536 is a inhibitor of adenylyl cyclase (IC50 = 1.4 μM). |
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| DC10553 | ST034307 Featured | ST034307 is a potent and selective adenylyl cyclase 1 (AC1) inhibitor, with IC50 of 2.3 μM. |
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| DC7573 | STF-118804 Featured | STF-118804 is a highly specific NAMPT inhibitor. |
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| DC9125 | Sumatriptan succinate | Sumatriptan succinate is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache. |
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| DC8267 | SW033291 Featured | SW033291 is a potent inhibitor of 15-PGDH enzyme with IC50 value of 1.5 nM and dissociation constant Ki app value of 0.1 nM. |
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| DC11781 | T-3764518 | T-3764518 (T 3764518, T3764518) is a novel potent, orally active SCD1 inhibitor with binding IC50 of 4.7 nM for hSCD1. |
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| DC8058 | T863 Featured | T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor |
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| DC5901 | Tadalafil Featured | Tadalafil is a potent and selective inhibitor of Phosphodiesterase-5 (PDE5) This compound prevents the breakdown of phosphodiesterases, many of which are used as secondary messengers. By preventing the breakdown of these messenger molecules, tadalafil can |
|
| DC7945 | TAK-063 Featured | TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs. |
|
| DC8739 | Talabostat mesylate | Talabostat mesilate(PT-100; Val-boroPro) is an orally active, specific inhibitor of dipeptidyl peptidases(IC50=1 nM for DPP4), including tumor-associated fibroblast activation protein. |
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| DC7769 | Tanomastat | Tanomastat is an angiogenesis and Matrix Metalloproteinase inhibitor |
|
| DC8131 | TAPI-2 (TNF Protease Inhibitor 2) Featured | TAPI-2 inhibits ADAM8, 10, 12, and TACE with Ki values of 10, 3, 100, and 0.12 µM, respectively. |
|
| DC9996 | TB5 Featured | TB5 is a potent, selective and reversible inhibitor of hMAO-B with a Ki value of 0.11±0.01 μM. |
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| DC9327 | Temocapril (hydrochloride) | Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
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| DC11661 | BAY 73-6691 | BAY 73-6691 is a drug developed by Bayer for the treatment of Alzheimer's disease. It was the first compound developed that acts as a phosphodiesterase inhibitor selective for the PDE9A subtype. |
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| DC11492 | GMX-1777 chloride | The water-soluble prodrug of GMX-1778 (CHS-828), which is a potent and specific inhibitor of the NAD(+) biosynthesis enzyme NAMPT with IC50 of <20 nM. |
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| DC9701 | Tipifarnib Featured | Tipifarnib (IND 58359; R115777) is a potent and specific farnesyltransferase inhibitor with an IC50 of 0.6 nM. |
|
| DC10149 | TM5275 sodium salt Featured | TM5275 is an orally available, potent and selective inhibitor of PAI-1 that delivers antithrombotic benefits devoid of bleeding effect in nonhuman primates. |
|
| DC10374 | TM5441 Featured | TM5441 is a novel orrally active TAP-1 antagonist. |
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| DC2080 | TMS Featured | TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. |
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| DC10381 | TOFA | TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ). |
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| DC8008 | TOK-001(Galeterone) Featured | TOK-001 is a multifunctional antiandrogen and CYP17 inhibitor(IC50=47 nM) in castration resistant prostate cancer (CRPC). |
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| DC11485 | Tolcapone Featured | Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. |
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| DC10088 | TPI-1 Featured | TPI-1 is a potent and selective SHP-1 inhibitor effective at low nanomolar levels. |
|
| DC8272 | U-104 Featured | U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM; low inhibition for CA I and CA II. |
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| DC7966 | U73122 Featured | U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase). |
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| DC4133 | Udenafil | Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) |
|
| DC10083 | UK-371804 Featured | UK-371804 is a potent and selective uPA inhibitor with excellent enzyme potency (Ki 10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin). |
|
| DC7335 | URB-597 Featured | URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. |
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| DC9990 | URB602 Featured | URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 µM for the rat brain enzyme. |
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