Cat. No. | Product name | CAS No. |
DC9110 |
Mevastatin
Mevastatin (Compactin; ML236B) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. |
73573-88-3 |
DC3158 |
Milrinone
Featured
Milrinone(Primacor) is a a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 μM for the inhibition of FIII PDE |
78415-72-2 |
DC8041 |
MK-0941
Featured
MK-0941 is a novel Glucokinase activator (GKA) |
1137916-97-2 |
DC7585 |
Omarigliptin
Featured
MK-3102 (MSD) is a novel DPP-4 Inhibitor, which improves glycaemic control with low risk of symptomatic hypoglycaemia. |
1226781-44-7 |
DC5034 |
MK8245
Featured
MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. |
1030612-90-8 |
DC9901 |
Verubecestat (MK-8931)
Featured
MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase. |
1286770-55-5 |
DC9874 |
ML-348(ML348)
Featured
ML 348(ML348) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). |
899713-86-1 |
DC10747 |
ML355
Featured
ML355 is a potent and selective inhibitors of 12-Lipoxygenase(12-LOX) with IC50 of 0.34 μM, excellent selectivity over related lipoxygenases and cyclooxygenases, and possess favorable ADME properties. |
1532593-30-8 |
DC12255 |
MLN-4760
Featured
MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM). |
305335-31-3 |
DC11368 |
MMP-2/MMP-9 Inhibitor II
MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively). |
193807-60-2 |
DC11343 |
MMP-2/MMP-9 Inhibitor III
MMP-2/MMP-9 inhibitor III is a cyclic peptide inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 10-20 μM for both). |
244082-19-7 |
DC11355 |
MMP-3 Inhibitor
Featured
MMP-3 inhibitor is a peptide inhibitor of matrix metalloproteinase-3 (MMP-3) with a Ki value of 95 nM. |
158841-76-0 |
DC9326 |
Moexipril (hydrochloride)
Moexipril HCl is a potent orally active non-sulfhydryl angiotensin converting enzyme(ACE) inhibitor, which is used for the treatment of hypertension and congestive heart failure. |
82586-52-5 |
DC7982 |
Mutant IDH1-IN-1
Featured
Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 uM(A level in Patent). |
1355326-21-4 |
DC7471 |
N6022
Featured
N6022 is a potent, selective, reversible, and efficacious S-Nitrosoglutathione reductase(GSNOR) inhibitor(IC50=10 nM) which is currently undergoing clinical development. |
1208315-24-5 |
DCAPI1460 |
Naratriptan hydrochloride
Naratriptan Hydrochloride is a triptan drug which is used for the treatment of migraine headaches. |
143388-64-1 |
DC8857 |
NCT-501
NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. |
1802088-50-1 |
DC12128 |
NCT-505
Featured
NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM, and weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 (IC50s, >57, 22.8, 20.1, >57 μM). |
2231079-74-4 |
DC10173 |
Firsocostat(ND-630,GS-0976)
Featured
ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. |
1434635-54-7 |
DC9046 |
Neostigmine bromide
Neostigmine Bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis. |
114-80-7 |
DCAPI1543 |
Neostigmine Methylsulfate
Neostigmine Methyl Sulfate is a reversible acetylcholinesterase inhibitor. This compound blocks the breakdown of acetylcholine in the synaptic space, leading to prolonged signaling and thus increased muscle contractions. |
51-60-5 |
DC5177 |
Nepicastat HCl (SYN-117)
Featured
Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. |
170151-24-3 |