| DC49765 |
Curcumin monoglucuronide |
Curcumin monoglucuronide is known as a glucuronic acid conjugate, which is one of the in vivo metabolites of curcumin. Curcumin monoglucuronide is used for research on the metabolism of curcumin and examination of its development as a pharmaceutical. Curcumin monoglucuronide has the potential for the research of cancer disease (extracted from patent WO2022004873A1). |
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| DC49766 |
Retinol-d4 |
Retinol-d4 (Vitamin A1-d4) is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite. |
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| DC49767 |
Paraherquamide E |
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects. |
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| DC49768 |
11-epi-Chaetomugilin I |
11-epi-Chaetomugilin I is a metabolite found in Chaetomium globosum. 11-epi-Chaetomugilin I exhibits significant cytotoxic activity against the murine P388 leukemia cell line, the human HL-60 leukemia cell line, the murine L1210 leukemia cell line, and the human KB epidermoid carcinoma cell line. |
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| DC49769 |
Ebaresdax hydrochloride |
Ebaresdax hydrochloride can inhibit peroxynitrite oxidation derived by SIN-1 and peroxynitrite mediated Cytotoxicity with IC50s of 3.7±0.80 and 0.13±0.02 uM, respectively. |
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| DC49770 |
H2S Donor 5a |
H2S Donor 5a is a cysteine-activated H2S donor. H2S plays important roles in biological systems. H2S Donor 5a is a useful tool in H2S research. |
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| DC49771 |
Magnesium acetate tetrahydrate |
Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt. As a salt form of Magnesium, Magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium acetate tetrahydrate can be used as an electrolyte supplementation or a reagent in molecular biology experiments. |
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| DC49772 |
Homovanillic acid-13C6,18O |
Homovanillic acid-13C6,18O is the 13C-labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. |
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| DC49773 |
5a-Pregnane-3,20-dione-d6 |
5a-Pregnane-3,20-dione-d6 is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite. |
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| DC49774 |
21-Deoxycortisol-d8 |
21-Deoxycortisol-d8 is the deuterium labeled 21-Deoxycortisol. 21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia. |
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| DC49775 |
Thiamine pyrophosphate-d3 |
Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. |
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| DC49776 |
5-Hydroxyindole-3-acetic acid-13C6 |
5-Hydroxyindole-3-acetic acid-13C6 is the 13C-labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. |
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| DC49777 |
Nicotinamide-13C6 |
Nicotinamide-13C6 (Niacinamide-13C6) is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1. |
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| DC49778 |
TMC-205 |
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter. |
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| DC49779 |
7-Hydroxypestalotin |
7-Hydroxypestalotin (LL-P880β) is a fungal metabolite. |
|
| DC49780 |
Vitamin K1-d4 |
Vitamin K1-d4 (Phylloquinone-d4) is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. |
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| DC49781 |
Cholic acid-13C |
Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. |
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| DC49782 |
1,3,7-Trimethyluric acid |
1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort. |
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| DC49783 |
(Rac)-sn-Glycerol 3-phosphate |
(Rac)-sn-Glycerol 3-phosphate is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited. |
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| DC49784 |
Murideoxycholic acid |
Murideoxycholic acid is a 6 beta-hydroxylated bile acid. |
|
| DC49785 |
Eicosapentaenoic Acid sodium |
Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation. |
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| DC49786 |
Phenylacetyl CoA |
Phenylacetyl CoA is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica. |
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| DC49787 |
2-Hydroxypalmitic acid |
2-Hydroxypalmitic acid is an intermediate in phytosphingosine metabolism. |
|
| DC49788 |
1-Aminopropan-2-ol |
1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas. |
|
| DC49789 |
Biliverdin hydrochloride |
Biliverdin hydrochloride is a tetrapyrrolic, water-soluble compound formed by the breakdown of heme. Biliverdin hydrochloride can upregulate the activity of biliverdin reductase which is an enzyme that is a regulator of the innate immune system. |
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| DC49790 |
Butyrolactone II |
Butyrolactone II is a fungal metabolite isolated from Aspergillus flavipes. |
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| DC49791 |
F-14329 |
F-14329 is a tetramic acid fungal metabolite. |
|
| DC49792 |
2-Hydroxyestrone-13C6 |
2-Hydroxyestrone-13C6 (Catecholestrone-13C6) is the 13C-labeled 2-Hydroxyestrone. 2-Hydroxyestrone (Catecholestrone) is a specific receptor-mediated antiestrogenic agent. 2-Hydroxyestrone is anticarcinogenic. |
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| DC49793 |
2-Methoxyestrone-13C6 |
2-Methoxyestrone-13C6 is the 13C-labeled 2-Methoxyestrone. 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81. |
|
| DC49794 |
Retinol-d6 |
Retinol-d6 (Vitamin A1-d6) is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite. |
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