Cat. No. | Product name | CAS No. |
DC23305 |
BM-1197
BM-1197 is a potent, specific dual inhibitor of Bcl-2 and Bcl-xL with Ki of <1 nM, shows >1,000-fold selectivity over Mcl-1. |
1391107-89-3 |
DC20802 |
BM-635
BM-635 is a small molecule anti-mycobacterial compound acting by inhibiting the mycobacterial membrane protein Large 3 (MmpL3). |
1073372-01-6 |
DC23304 |
BM-957
BM-957 is a highly potent, dual Bcl-2 and Bcl-xL inhibitor with Ki of <1 nM for both, IC50 of 5.4 and 6.0 nM, respectively. |
1391107-54-2 |
DC20321 |
Bm-MPK1-IN-15b
Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM. |
2222294-62-2 |
DC8452 |
BMN-673 8R,9S
BMN-673 (8R,9S) is the (8R,9S) enantiomer of BMN-673. BMN 673 is a novel PARP inhibitor with IC50 of 0.58 nM(PARP1). It does not inhibit PARG and is highly sensitive to PTEN mutation. |
1207456-00-5 |
DC23833 |
SB 4 (Eticovo)
Featured
BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes. |
100874-08-6 |
DC20812 |
BMS 695735
BMS 695735 is a potent, selective IGF-1R inhibitor with IC50 of 34 nM. |
1054315-48-8 |
DC11761 |
BMS-816336
A novel potent, selective, orally active human 11β-HSD1 inhibitor with IC50 of 3.0 nM. |
1009583-20-3 |
DC22988 |
BMS-189453
Featured
BMS-189453 (BMS189453, BMS453) is a synthetic retinoid that acts as an agonist of RARβ and an antagonist of RARα and RARγ. |
166977-43-1 |
DC8515 |
BMS-2
BMS-2 is a potent MET kinase inhibitor with an IC50 value of 1.8nM. It also possesses potent inhibitory activity against Flt-3 and VEGFR-2 kinases, IC50 values of 4nM and 27nM respectively. |
888719-03-7 |
DC22032 |
BMS-211
BMS-211 is a prodrug of the parent pan-CK2 inhibitor BMS-699.. |
|
DC11294 |
BMS-212
BMS-212 is a potent and selective stimulator of glucokinase (GK) (EC50 = 35 nM) that is promisingly used as an antidiabetic. |
2173153-38-1 |
DC10200 |
BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor with potent antitumor activity with an IC50 of 1.35 nM. |
195987-41-8 |
DC8762 |
BMS-265246
BMS-265246 is a potent and selective CDK1/2 inhibitor for CDK1/cyclin B and CDK2/cyclin E with IC50 of 6 nM and 9 nM, respectively. |
582315-72-8 |
DC20808 |
BMS-394136
BMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles.. |
343246-73-1 |
DC20809 |
BMS433771
BMS433771 is a potent, orally active RSV fusion inhibitor, exhibits excellent potency against multiple laboratory and clinical isolates of both group A and B viruses with mean EC50 of 20 nM. |
543700-68-1 |
DC23529 |
BMS-457
BMS-457 is a potent and selective CCR1 antagonist with binding IC50 of 0.8 nM, >1,000-fold selectivity against other CC family receptors. |
946594-19-0 |
DC7007 |
BMS-538203
BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent. |
543730-41-2 |
DC23167 |
BMS-564929
BMS-564929 is a potent, selective androgen receptor modulator (SARM) that binds to AR with Ki of 2.11 nM. |
627530-84-1 |
DC22033 |
BMS-595
BMS-595 (BMS595) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 1.3 nM (CKα). |
|
DC24131 |
BMS-599626 hydrochloride
BMS-599626 (AC-480) is a potent, selective inhibitor of EGFR and HER2 with IC50 of 20 nM and 30 nM. |
873837-23-1 |
DC20805 |
BMS-641988
BMS-641988 is a potent, selective, nonsteroidal androgen receptor antagonist with Ki of 1.7 nM, MDA-MB-453 cell IC50 of 16 nM. |
573738-99-5 |