Cat. No. | Product name | CAS No. |
DC20811 |
BMS-654457
BMS-654457 is a potent, reversible and direct inhibitor of factor XIa (FXa) with Ki of 0.4 nM. |
1004551-41-0 |
DC22034 |
BMS-699
BMS-699 (BMS699) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 0.1 nM (CKα). |
|
DC23482 |
BMS-741672
BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.. |
1004757-96-3 |
DC20813 |
BMS-751324
BMS-751324 is a novel clinical prodrug of BMS-582949, which is a highly selective p38α MAPK inhibitor with IC50 of 13 nM. |
948842-66-8 |
DC9861 |
BMS-779788(XL-652)
Featured
BMS-779788(XL652) is a novel small-molecule modulator of the Liver X Receptor (LXR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic disorders. |
918348-67-1 |
DC9638 |
BMS-794833
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7/15 nM; also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. |
1174046-72-0 |
DC20814 |
BMS-795311
BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM. |
939390-99-5 |
DC7089 |
BMS-806 (BMS 378806)
BMS-806 (BMS 378806) is a small molecule gp120/CD4 inhibitor with an IC50 of median 5 nM. |
357263-13-9 |
DC10494 |
BMS813160
Featured
BMS-813160 is a dual CCR2/CCR5 chemokine antagonist. |
1286279-29-5 |
DC23526 |
BMS-817399
BMS-817399 is a potent, selective, orally bioavailable CCR1 antagonist with binding IC50 of 1 nM, inhibits MIP-1α-induced chemotaxis with IC50 of 6 nM. |
1202400-18-7 |
DC12635 |
BMS-818251
BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3. |
|
DC12512 |
BMS-823778 free base
BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2. |
1140897-32-0 |
DC7154 |
BMS-833923 (XL-139)
Featured
BMS 833923 is an orally bioavailable inhibitor of Smo. It blocks binding of BODIPY cyclopamine (IC50 = 21 nM) and inhibits Gli activation in cell lines that express wild-type Smo or activated mutant forms of Smo (IC50s = 6-35 nM). BMS 833923 robustly inhi |
1059734-66-5 |
DC23891 |
BMS-869780
BMS-869780 is a potent γ-secretase modulator (GSM) that decreases Aβ1-42 (IC50=5.1 nM) and Aβ1-40 (IC50=25.1 nM) and increases Aβ1-37 and Aβ1-38 without inhibiting overall levels of Aβ peptides or other APP processing intermediates. |
1235493-78-3 |
DC20817 |
BMS-871
BMS-871 is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively. |
1584631-89-9 |
DC20818 |
BMS-884775
BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM. |
1557206-59-3 |
DC11990 |
BMS-901715
BMS-901715 is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor.. |
1699861-37-4 |
DC11862 |
BMS-906024
BMS-906024 is a highly potent, selective inhibitor of γ-secretase mediated signaling of Notch1/2/3/4 receptors with IC50 of 1.6/0.7/3.4/2.9 nM, respectively. |
1401066-79-2 |
DC20819 |
BMS-919373
BMS-919373 is a potent I(Kur)/Kv1.5 channel blocker with IC50 of 50 nM, with selectivity versus hERG, Na, Ca channels and reduced the level of brain penetration. |
1272353-82-8 |
DC22445 |
BMS-933043
BMS-933043 is a novel highly selective, potent α7 nAChR partial agonist with binding Ki of 3.3 and 8.1 nM for rat and human α7, respectively. |
1221973-93-8 |
DC23411 |
BMS-952048(BMS952048;BMS 952048)
BMS-952048 is a positive allosteric modulator of mGluR5 with EC50 of 10 nM.. |
1375751-32-8 |
DC20820 |
BMS-961955
BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively. |
1431328-92-5 |