| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21010 | FF-10501-01 | FF-10501-01 is a potent, selective and orally available IMPDH inhibitor. |
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| DC10973 | FF-10502 | FF-10502 (FF-10502-01) is a pyrimidine nucleoside antimetabolite that shows growth inhibition of pancreatic cancer cell lines with IC50 of 60-330 nM. |
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| DC23627 | FFN-206 dihydrochloride | FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling |
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| DC10128 | FGF401( Roblitinib) Featured | FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. |
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| DC9933 | FGFR4-IN-1 | FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM. |
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| DC21012 | FGI-103 | FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
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| DC21013 | FGI-104 | FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
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| DC20384 | Fhit-IN-15 | Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells.. |
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| DC20385 | FICZ Featured | FICZ is a high affinity aryl hydrocarbon receptor (AhR) agonist with Kd of 70 pM. |
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| DC21673 | Fidarestat | Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats.. |
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| DC21817 | Filaminast | Filaminast (WAY-PDA-641. |
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| DC21482 | Filibuvir | Filibuvir (PF-00868554. |
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| DC11432 | FimH inhibitor 5h | FimH inhibitor 5h is a potent and orally active FimH inhibitor. |
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| DC8847 | Finafloxacin (BAY35-3377) Featured | Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. |
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| DC23501 | Finazine | Finazine is a high-affinity, brain penetrant sigma-1 and sigma 2 receptor ligand with Ki of 2.6 nM and 46 nM, respectively. |
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| DC12637 | Finerenone Featured | Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease. |
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| DC8936 | Fingolimod | Fingolimod(FTY720 free base) is a S1P antagonist with IC50 of 0.033 nM. |
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| DC11309 | Fipronil | Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 and 1,600 nM for cockroach and rat receptors, respectively). |
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| DC8917 | Firocoxib | Firocoxib(ML 1785713) is a potent and selective cyclooxygenase (COX)-2 inhibitor with IC50 of 0.13 uM, 58 fold sensitivity for COX2 VSCOX1. |
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| DC21015 | FIT-039 Featured | FIT-039 is a potent, selective CDK9 inhibitor with IC50 of 5.8 uM for CKD9/cyclin T1, suppresses the replication of HSV-1 (IC50=0.69 uM). |
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| DC20386 | Pioglitazone Featured | Pioglitazone is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. |
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| DC21016 | FJ 5002 | FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077. |
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| DC22093 | FKGK18 | FKGK18 (FKGK18) is a potent, selective inhibitor of iPLA2 (group VIA Ca2+-independent phospholipase A2) with IC50 of 50 nM. |
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| DC20019 | Flagelin 22(TFA) (Flagellin 22(TFA)) | Flagelin 22 TFA, a fragment of bacterial flagellin, is an effective elicitor in both plants and algae. |
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| DC10972 | Flavokawain B | Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression. |
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| DC2014 | Flavopiridol Featured | Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM, and CDK7 with IC50 of 300 nM. |
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| DC9623 | Flecainide (acetate) Featured | Flecainide(Tambocor) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential. |
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| DC9321 | Flibanserin Featured | Flibanserin is a novel multifunctional serotonin agonist and antagonist (MSAA) that improves sexual functioning in premenopausal women who suffer from reduced sexual interest and desire. |
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| DC8726 | FLLL31 Featured | FLLK31 is a potent and selective inhibitor of the STAT3 signaling pathway. |
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| DC11780 | FLT3-IN-5e | FLT3-IN-5e is a nove potent, selective FLT3 inhibitor with Kd of 3.6 nM, IC50 of <6 nM. |
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