| DC9350 |
Faropenem daloxate |
Faropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.
|
|
| DC20380 |
Faropenem |
Faropenem is an orally active beta-lactam antibiotic with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes. |
|
| DC24118 |
C75
Featured
|
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM). |
|
| DC20381 |
Fasentin
Featured
|
Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1. |
|
| DC22759 |
FAS-IN-1 |
FAS-IN-1 is a potent inhibitor of fatty acid synthase (FAS) wtih IC50 of 10 nM.. |
|
| DC10403 |
FAS-IN-1 Tosylate |
FAS-IN-1 tosylate is a potent inhibitor of fatty acid synthase (FAS) extracted from patent WO 2012064642 A1, compound 29; has an IC50 of 10 nM. |
|
| DC23119 |
FB23-2(FTO Demethylase inhibitor FB23-2)
Featured
|
FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM. |
|
| DC23678 |
FCPR03 |
FCPR03 is a novel potent, selective PDE4 inhibitor with IC50 of 60, 31 and 47 nM for PDE4CAT (PDE4 catalytic domain), PDE4B1 and PDE4D7, respectively. |
|
| DC25015 |
FD-44 |
FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model. |
|
| DC26037 |
FDL-169
Featured
|
FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector being developed by Flatley Discovery Lab for treating cystic fibrosis (CF) patients who carry the F508del mutation |
|
| DC20382 |
FEN1-IN-1 |
FEN1-IN-1 is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM. |
|
| DC20383 |
FEN1-IN-C20 |
FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM. |
|
| DC8684 |
Fenoxaprop-P-ethyl
Featured
|
Fenoxaprop-P-ethyl is a post-emergent phenoxy herbicide of the aryloxyphenoxy propionate group. |
|
| DC12246 |
Feretoside |
Feretoside, a phenolic compound extracted from the barks of E. ulmoides, is a HSP inducer which act as cytoprotective agent. |
|
| DC20102 |
Ferulic acid methyl ester
Featured
|
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical s |
|
| DC23516 |
Fesoterodine |
Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. |
|
| DC23515 |
Fesoterodine maleate |
Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. |
|
| DC8912 |
Fesoterodine fumarate
Featured
|
Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist. |
|
| DC21010 |
FF-10501-01 |
FF-10501-01 is a potent, selective and orally available IMPDH inhibitor. |
|
| DC10973 |
FF-10502 |
FF-10502 (FF-10502-01) is a pyrimidine nucleoside antimetabolite that shows growth inhibition of pancreatic cancer cell lines with IC50 of 60-330 nM. |
|
| DC23627 |
FFN-206 dihydrochloride |
FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling |
|
| DC10128 |
FGF401( Roblitinib)
Featured
|
FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. |
|
| DC9933 |
FGFR4-IN-1 |
FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM. |
|
| DC21012 |
FGI-103 |
FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
|
| DC21013 |
FGI-104 |
FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
|
| DC20384 |
Fhit-IN-15 |
Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells.. |
|
| DC20385 |
FICZ
Featured
|
FICZ is a high affinity aryl hydrocarbon receptor (AhR) agonist with Kd of 70 pM. |
|
| DC21673 |
Fidarestat |
Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats.. |
|
| DC21817 |
Filaminast |
Filaminast (WAY-PDA-641. |
|
| DC21482 |
Filibuvir |
Filibuvir (PF-00868554. |
|
