Cat. No. | Product name | CAS No. |
DC23143 |
BMS-983970
BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models.. |
1584713-87-0 |
DC22035 |
BMS-984923
BMS-984923 (BMS-984923) is a potent silent allosteric modulator (SAM) of mGluR5 with competitive antagonism of MPEPy binding with Ki of 0.6 nM, but has no detectable agonist and antagonist activity at mGluR5 signaling. |
1375755-46-6 |
DC23873 |
BMS-986115
BMS-986115 is an orally bioavailable, γ-secretase and pan-Notch inhibitor with potential antineoplastic activity. |
1584647-27-7 |
DC23459 |
BMS-986118
BMS-986118 is a potent and selective GPR40 agonist with EC50 of 70 and 63 nM for hGPR40 and mGPR40, shows no PPARγ activity (EC50>47 uM). |
1610562-74-7 |
DC26073 |
BMS-986122
Featured
BMS-986122 is a potent positive allosteric modulator of μ-opioid receptor, significantly increases the inhibition of forskolin-stimulated adenylyl cyclase activity produced by an EC10 (30 pM) concentration of endomorphin-I in CHO-μ cells.. |
313669-88-4 |
DC23609 |
BMS-986163
BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM).. |
1801151-09-6 |
DC12174 |
Deucravacitinib(BMS986165)
Featured
BMS-986165 is a selective, potent, allosteric inhibitor of tyrosine kinase 2 (Tyk2). |
1609392-27-9 |
DC23639 |
BMS-986169
BMS-986169 is a novel GluN2B negative allosteric modulator, demonstrates high binding affinity for the GluN2B allosteric site (Ki=4.0 nM) and selective inhibition of GluN2B receptor function (IC50=24 nM) in cells. |
1801151-08-5 |
DC23460 |
BMS986187
Featured
BMS-986187 is a novel potent, positive allosteric modulator of δ-opioid receptor with EC50 of 30 nM, 100-fold selectivity over μ-opioid receptor.. |
684238-37-7 |
DC10924 |
BMS986202
Featured
BMS-986202 is a clinical Tyk2 inhibitor that binds to Tyk2 JH2 with IC50 of 0.19 nM and shows remarkably selectivity over other kinases including Jak family members. |
|
DC22036 |
BMT-046091
BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM. |
1551401-20-7 |
DC11989 |
BMT-090605
BMT-090605 (BMT 090605, BMT090605) is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50 0.6 nM. |
1551403-51-0 |
DC9937 |
BMT-145027
BMT-145027 is a potent mGluR5 PAM with no inherent mGluR5 agonist activity. |
2018282-44-3 |
DC23998 |
BMX-IN-1
Featured
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity. |
1431525-23-3 |
DC7377 |
BMY 7378
Featured
BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3. |
21102-95-4 |
DC23754 |
BNC-1
BNC-1 is a small molecule modulator of Amyloid pathology by promoting phosphorylation and activation of Elk-1, a transcriptional repressor of presenilin-1 but not presenilin-2. |
96335-59-0 |
DC7773 |
BNC-105
Featured
BNC105 is a novel tubulin polymerization inhibitor that selectively disrupts tumor vasculature and displays single-agent antitumor efficacy. |
945771-74-4 |
DC23262 |
BNM-III-170
BNM-III-170 is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo. |
1859189-54-0 |
DC23243 |
BNM-III-170 trifluoroacetate
BNM-III-170 TFA salt is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo. |
1859189-55-1 |
DC20823 |
BNS-22
BNS-22 is a small-molecule inhibitor of DNA topoisomerase II, inhibits kinetoplast DNA decatenation that is mediated by human TOP2α and TOP2β in vitro with IC50 of 2.8 and 0.42 uM, respectively. |
1151668-24-4 |
DC20034 |
Boc-MLF TFA
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations. |
|
DC9547 |
Boldenone Undecylenate
Boldenone undecylenate(Equipoise) is a synthetic steroid which has a similar effect as the natural steroid testosterone; it is frequently used in veterinary medicine, though it is also used in humans. |
13103-34-9 |