| DC22971 |
CDE 096 |
A selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
|
| DC21780 |
UNC-3230 |
A selective, small molecule inhibitor of PIP5K1C with IC50 of 41 nM, does not ihibits other lipid kinases including PI3Ks. |
|
| DC21400 |
NS-1209 |
A selective, water-soluble, in vivo long-lasting AMPA antagonist with Ki of 43 nM. |
|
| DC22451 |
AQX 1125 acetate |
A sepecific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM. |
|
| DC23981 |
BCX-1470 methanesulfonate
Featured
|
A serine protease inhibitor that inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM). |
|
| DC22666 |
Levosalbutamol |
A short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).. |
|
| DC23231 |
Levalbuterol tartrate |
A short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).. |
|
| DC22828 |
DBCO-Amine |
A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond. |
|
| DC23011 |
Shz-1 |
A small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells. |
|
| DC25018 |
Shz-3 |
A small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells. |
|
| DC21818 |
MIN-117 |
A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.. |
|
| DC22831 |
VU 0038882 |
A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism. |
|
| DC23648 |
TKN2 |
A small molecule allosteric inhibitor of TREK channels with IC50 of 3.8, 1.7 and 10.3 uM for TREK-1, TREK-2 and TRAAK, respectively.. |
|
| DC23585 |
28NH |
A small molecule allosteric inhibitor of TREK channels with IC50 of 5.0, 5.0 and 11.8 uM for TREK-1, TREK-2 and TRAAK, respectively.. |
|
| DC23582 |
TKN1 |
A small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.. |
|
| DC23241 |
TAME |
A small molecule anaphase-promoting complex/cyclosome (APC/C) inhibitor that binds to the APC preferentially suppresses APC/C(Cdc20) rather than APC/C(Cdh1). |
|
| DC11655 |
ABO dihydrochloride |
A small molecule ANXA7 GTPase activity inhibitor, induces mouse ESCs differentiation to VECs. |
|
| DC24017 |
SMER-18 |
A small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein. |
|
| DC11668 |
AUTEN-67 |
A small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14. |
|
| DC23190 |
LM22A-4 |
A small molecule BDNF mimetic that act as a direct and specific partial agonist of TrkB (EC50=200-500 pM), but not p75. |
|
| DC25021 |
Endosidin-2
Featured
|
A small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.. |
|
| DC22842 |
DMJ-I-228 |
A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.. |
|
| DC11698 |
α-NETA |
A small molecule CMKLR1 antagonist that inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 (EC50=9.7 nM). |
|
| DC22524 |
ZSET1446 |
A small molecule cognitive enhancer that potentiates acetylcholine-mediated facilitation of inhibitory synaptic transmission in the hippocampal neurons. |
|
| DC9867 |
prostaglandin D2（PGD2) inhibitor
Featured
|
A small molecule compound of prostaglandin D2（PGD2) inhibitor. |
|
| DC12003 |
Corr4A
Featured
|
A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.. |
|
| DC20445 |
Me6TREN |
A small molecule Cu complexing ligand used for atom transfer radical polymerization (ATRP). |
|
| DC21067 |
TB-03 |
A small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774). |
|
| DC22843 |
DDX3-IN-16d
Featured
|
A small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses. |
|
| DC11645 |
Pitstop 2
Featured
|
A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis. |
|
