| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC1050 | Daptomycin Featured | Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms. |
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| DC3152 | Darifenacin | Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9. |
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| DC8908 | Darunavir ethanolate Featured | Darunavir ethanolate is an HIV protease inhibitor,showed potent activity against COVID-19(SARS-COV-2). |
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| DC21381 | Dasolampanel | Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.. |
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| DC9331 | Daun02 | Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction. |
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| DC7069 | Daunorubicin HCL Featured | Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. |
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| DC25058 | Daunorubicin Featured | Daunorubicin is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells. |
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| DC20942 | DB04760 | DB04760 is a potent, highly selective, non–zinc-chelating MMP-13 inhibitor with IC50 of 8 nM, displays high selectivity over other MMPs. |
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| DC22067 | DB1055 | DB1055 (DB-1055, DB 1055) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence. |
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| DC20943 | DB2115 | DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
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| DC23251 | DB213 Featured | DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication. |
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| DC12516 | DB550 | DB550 (DB-550) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction without affecting the CD95-FADD interaction binds to SH3-PLCγ1 with Kd of 40.7 uM. |
|
| DC12517 | HT105 | DB550 (DB-550, TCWKHRK) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction, abrogates the CD95-mediated Ca2+ response in mouse PBLs with IC50 of 38 nM. |
|
| DC22069 | DB818 Featured | DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence. |
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| DC21882 | DBCO acid 1 | DBCO acid 1 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21883 | DBCO acid 2 | DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21884 | DBCO acid 3 | DBCO acid 3 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21885 | DBCO acid 4 | DBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21886 | DBCO acid 5 | DBCO acid 5 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21888 | DBCO intermidate 1 | DBCO intermidate 1 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21889 | DBCO intermidate 2 | DBCO intermidate 2 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21890 | DBCO intermidate 3 Featured | DBCO intermidate 3 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21891 | DBCO Maleimide | DBCO Maleimide is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC20355 | DBCO-NHS ester 2 | DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry. |
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| DC22076 | DBCO-NHS ester 3 | DBCO-NHS ester 3 (DIBAC-NHS) is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21987 | DBCO-PEG4 amine | DBCO-PEG4 amine (ADIBO-PEG4-amine) is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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| DC21892 | dBET23 | dBET23 is a BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=50 nM) in cellular degradation assays.. |
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| DC21893 | dBET57 Featured | dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=500 nM), but is inactive on BRD4 BD2.. |
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| DC8108 | DBPR108 | DBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM; no inhibition on DDP8 and DPP9. IC50 value: 15 Nm. |
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| DC7790 | CB1-IN-1(BPRCB1184) Featured | CB1-IN-1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0.3 nM (Ki, CB1R) 21 nM (Ki, CB2R) Target: CB1R in vivo: CB1-IN-1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. CB1-IN-1 has great potential to ameliorate this related metabolic syndrome. |
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