| DC23791 |
Deoxyspergualin |
Deoxyspergualin is a derivative of the antitumor antibiotic spergualin that binds specifically to Hsc70, also inhibits poly(rC) binding protein 2 (PCBP2).. |
|
| DC8911 |
Deracoxib |
Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). |
|
| DC10559 |
Derazantinib (ARQ 087)
Featured
|
Derazantinib (Derazantinib) is an ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC50s of 4.5, 1.8, and 4.5 nM, respectively. |
|
| DC11055 |
Desmethyl dabrafenib
Featured
|
Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo.. |
|
| DC11331 |
Desoximetasone |
Desoximetasone is a glucocorticoid. |
|
| DC9631 |
Desvenlafaxine (succinate hydrate) |
Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI). |
|
| DC8097 |
Detomidine hydrochloride |
Detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist |
|
| DC10231 |
D panthenol |
Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. |
|
| DC23104 |
D-Fagomine |
D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively. |
|
| DC22187 |
DFMO |
DFMO (Ornithine Decarboxylase inhibitor DFMO) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis. |
|
| DC22074 |
DFP00173
Featured
|
DFP00173 (DFP-00173) is a potent and selective aquaporin-3 (AQP3) inhibitor, inhibits glycerol permeability in
erythrocytes with IC50 of 0.2 uM.. |
|
| DC24079 |
DG-172 dihydrochloride
Featured
|
DG-172 is a novel PPARβ/δ-selective ligand showing high binding affinity (IC50= 27 nM) and potent inverse agonistic properties. |
|
| DC20357 |
D-G23 |
D-G23 is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5.8 uM, binds to RAD52 with Kd of 34 uM and inhibits D-loop formation with IC50 of 7.2 uM in vitro. |
|
| DC9414 |
DGAT-1 inhibitor 2 |
DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1;antiobesity agents.
|
|
| DC23686 |
DGAT1-IN-1 |
DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM.. |
|
| DC20358 |
DGAT2 inhibitor 2 |
DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM). |
|
| DC20953 |
DH-376 |
DH-376 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM and 3-8 nM, respectively. |
|
| DC20937 |
D-I03 |
D-I03 (D-103) is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5 uM, binds to RAD52 with Kd of 25.8 uM and inhibits D-loop formation with IC50 of 8 uM in vitro. |
|
| DC20954 |
DI-404 |
DI-404 is a highly potent, peptidomimetic inhibitor of DCN1-UBC12 protein-protein interaction that bind to DCN1 protein with Kd of 6.9 nM, selectively inhibits the neddylation of cullin 3 over other cullin members. |
|
| DC11500 |
DI-591 |
DI-591 (DI591) is a potent, selective, cell-permeable inhibitor of the DCN1-UBC12 interaction with Ki of 10-12 nM for human DCN1 and DCN2. |
|
| DC12077 |
Diacylglycerol acyltransferase inhibitor-1 |
Diacylglycerol acyltransferase inhibitor-1 is a diacylglycerol acyltransferase (DGAT1) inhibitor. |
|
| DC10060 |
Dianilinopyrimidine_01(CZC8004)
Featured
|
Dianilinopyrimidine_01 is a Pan Tyrosine kinase inhibitor. |
|
| DC23201 |
Diarylpropionitrile
Featured
|
Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand, demonstrates the neuroprotective effects against 10 0M Aβ1-42-induced oxidative stress and inflammation in primary rat cortical cell culture. |
|
| DC23747 |
Diazepinomicin |
Diazepinomicin (TLN 4601. |
|
| DC10270 |
Diazoxide |
Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions. |
|
| DC20153 |
Dibutyl phthalate
Featured
|
Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects. |
|
| DC8918 |
Diclazepam |
Diclazepam(Ro5-3448; Chlorodiazepam) is an analogue of diazepam; are similar to diazepam, possessing anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties. |
|
| DC20359 |
Dicycloplatin |
Dicycloplatin (DCP) is a novel platinum analog that demonstrates significant antitumor activity against a variety of human cancer cell lines with IC50 of 25-30 nM. |
|
| DC9481 |
Didanosine |
Didanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.
Target: NRTIs; HIV
Didanosine is a dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. |
|
| DC22178 |
Didemethylclomipramine |
Didemethylclomipramine (Norclomipramine, N-Desmethylcomipramine) is the major active metabolite of the tricyclic antidepressant (TCA) clomipramine. |
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