Cat. No. | Product name | CAS No. |
DC8895 |
benzbromaron
Featured
Benzbromarone is a highly effective and well tolerated non-competitive inhibitor of xanthine oxidase, used as an uricosuric agent, used in the treatment of gout. |
3562-84-3 |
DC10459 |
BMS-986020
Featured
BMS-986020 is an LPA1 antagonist. |
1257213-50-5 |
DC11354 |
Carteolol (hydrochloride)
Carteolol is an antagonist of β-adrenergic receptors (Kd = 13 nM). |
51781-21-6 |
DC4160 |
CB-03-01
Featured
CB-03-01 is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use. |
19608-29-8 |
DC10868 |
Cilofexor
Featured
Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models. |
1418274-28-8 |
DC9183 |
Clomiphene citrate
Clomifene Citrate is a selective estrogen receptor modulator. |
50-41-9 |
DCAPI1091 |
Conivaptan hydrochloride
Featured
Conivaptan(YM 087) is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively. |
168626-94-6 |
DC4132 |
CP-547632
Featured
CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). |
252003-65-9 |
DC9278 |
CWHM-12
Featured
CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1. |
1564286-55-0 |
DC11082 |
Danicopan (ACH-4471)
Featured
Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM. |
1903768-17-1 |
DC9116 |
Dantrolene sodium
Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. |
14663-23-1 |
DC8188 |
Daprodustat
Featured
Daprodustat(GSK1278863) isa HIF-prolyl hydroxylase inhibitor. |
960539-70-2 |
DCAPI1107 |
Deferasirox (Exjade)
Featured
Deferasirox (Exjade) |
201530-41-8 |
DC9604 |
Desogestrel
Featured
Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP). |
54024-22-5 |
DC9434 |
DMP 777
DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor. |
157341-41-8 |
DC8485 |
E-64d(Aloxistatin)
Featured
E-64D is an inhibitor of cathepsins B and L; also thought to inhibit calpain,showed a potent activity for COVID-19(SARS-COV-2)with EC50: MERS-COV(1.275),SARS-COV(0.760) |
88321-09-9 |
DC10939 |
Edasalonexent
Edasalonexent (CAT-1004) is a bifunctional, orally administered small molecule that covalently links 2 compounds known to inhibit NF‐κB, salicylic acid and docosahexaenoic acid (DHA). |
1204317-86-1 |
DC8626 |
Eluxadoline
Featured
Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
864821-90-9 |
DC9771 |
ACU4429,ACU 4429,ACU-4429
Featured
Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. |
1141934-97-5 |
DC10314 |
Emixustat
Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro. |
1141777-14-1 |
DC9762 |
Emricasan
Featured
Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspase inhibitor. |
254750-02-2 |
DC11433 |
Vatiquinone
EPI-743 (Vatiquinone,EPI-589) is an orally bioavailable para-benzoquinone for treatment of inherited mitochondrial diseases, an analogue of the antioxidant ubidecarenone. |
1213269-98-7 |