| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10205 | Ilaprazole Featured | Ilaprazole (IY-81149) is a proton pump inhibitor; inhibits H+/K+-ATPase with an IC50 of 6.0 μM. |
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| DC7430 | Obeticholic acid (INT-747) Featured | INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity. |
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| DC7172 | IOWH-032 | iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays. |
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| DC4128 | Ivacaftor (VX-770) Featured | Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. |
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| DC12374 | JNJ-10229570 Featured | JNJ-10229570 (JNJ10229570) is a novel potent, selective melanocortin receptor MC1R and MC5R antagonist with binding IC50 of 270 nM and 200 nM, respectively. |
|
| DC10853 | LAU159 Featured | LAU159 is a novelα6β3γ2 GABAA receptor inhibitor. |
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| DC12386 | Leniolisib (CDZ173) Featured | Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor currently in phase II/III clinical trials for the treatment of immunodeficiency disorders. |
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| DC7633 | Ligandrol (VK5211, LGD-4033) Featured | Ligandrol (LGD-4033) is a novel nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity. |
|
| DC9938 | Lusutrombopag（S-888711） Featured | Lusutrombopag（S-888711） is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. |
|
| DC11524 | Mavacamten（MYK-461） Featured | Mavacamten（MYK-461）is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain. |
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| DC9527 | Methylnaltrexone (Bromide) Featured | Methylnaltrexone Bromide is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation. |
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| DC9995 | MGL-3196(Resmetirom) Featured | MGL-3196 is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia. |
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| DC10326 | Mozavaptan | Mozavaptan (OPC31260) is a orally effective, nonpeptide vasopressin V2 receptor antagonist with an IC50 of 14 nM. |
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| DC10173 | Firsocostat(ND-630,GS-0976) Featured | ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. |
|
| DCAPI1342 | Nepafenac | Nepafenac |
|
| DC9520 | NKP608 | NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo. |
|
| DC12298 | Octreotide acetate (SMS 201-995 (acetate)) Featured | Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently. |
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| DC11096 | Olacaftor | Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.. |
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| DC8390 | Oltipraz Featured | Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3. |
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| DC10299 | Olumacostat glasaretil | Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). |
|
| DC11044 | Omidenepag Isopropyl Featured | Omidenepag Isopropyl (DE-117, OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor; demonstrates excellent IOP-lowering activities following ocular administration in ocular normotensive monkeys, Omidenepag Isopropyl (OMDI) is a clinical candidate for the treatment of glaucoma. |
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| DC9876 | Pantoprazole | Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
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| DC9135 | Pantoprazole Sodium | Pantoprazole sodium salt(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
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| DC11100 | PBI-4050 sodium | PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
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| DC11099 | PBI-4050 | PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
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| DC8353 | PF-04418948 Featured | PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM). |
|
| DCAPI1305 | Pramiracetam | Pramiracetam |
|
| DC9162 | Ranolazine HCl Featured | Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP). |
|
| DC1048 | Rapamycin (Sirolimus) Featured | Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM. - |
|
| DC8185 | Verosudil(AR-12286) | Rho-kinase (ROCK) inhibitor |
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